Worsening functional status in nephrogeriatrics needs to be accounted for when clinically assessing CKD advancement in addition to GFR; supporting evidence based on the practical application of theoretical modelling

Table 3 ANOVA performed on variables between groups divided according to GFR and function testing

	Units	Intra-group variation	f	Inter- group variation	df	F	p-value	η²	Int
Creatinine	mg/dl	329.1	2	188.6	10	95.9	< 0.005	0.635	Large
Urea	mg/dl	144,064.9	2	122,889.8	10	64.4	< 0.005	0.539	Large
GFR	ml/min/1,73m²	62,245.8	2	23,286	10	147	< 0.005	0.727	Large
Age	years	2883.9	2	3752.2	10	42.2	< 0.005	0.434	Large
Comorbidities	number of diseases	118.8	2	469.7	10	13.9	< 0.005	0.201	Large
Medication	number of drugs	461.6	2	909.4	10	27.9	< 0.005	0.336	Large
Tinetti	points	1475	2	3252.3	10	24.9	< 0.005	0.312	Large
IADL	points	101.9	2	241.8	10	23.1	< 0.005	0.296	Large
Barthel	points	6267	2	33,505.2	10	10.2	< 0.005	0.157	Large

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