# Table 5 Case-fatality rate (CFR) in patients ≥ 80 years of age hospitalized with COVID-19

No. of deaths/Total No. of Patients

% of total deaths

CFR %

OR (95% CI)

p value

Total

80–84 years

818/2271

33.1

36.0

Ref

85–90 years

921/2106

37.2

43.7

1.38 (1.22–1.55)

< 0.001

90–94 years

538/1185

21.8

45.4

1.47 (1.38–1.70)

< 0.001

≥ 95 years

196/391

7.9

50.1

1.78 (1.43–2.21)

< 0.001

Total

2473/5953

100

41.5

First wave

80–84 years

685/1772

34.2

38.7

Ref

85–90 years

750/1622

37.4

46.2

1.36 (1.19–1.56)

< 0.001

90–94 years

413/864

20.6

47.8

1.45 (1.23–1.71)

< 0.001

≥ 95 years

156/287

7.8

54.4

1.89 (1.47–2.42)

< 0.001

Total

2004/4545

100

44.1

Successive waves

80–84 years

133/499

28.4

26.7

Ref

85–90 years

171/484

36.5

35.3

1.50 (1.14–1.97)

0.003

90–94 years

125/321

26.7

38.9

1.75 (1.30–2.37)

< 0.001

≥ 95 years

40/104

8.5

38.5

1.72 1.10–2.67)

0.016

Total

469/1408

100

33.3

-

Differences between first and successive waves*

95% (CI)*

p value**

80–84 years

-

-

-

-12.0 (-7.4; -16.4)

< 0.001

85–90 years

-

-

-

-10.9 (-5.9; -13.2)

< 0.001

90–94 years

-

-

-

-8.9 (-2.5, -15.0)

0.006

≥ 95 years

-

-

-

-15.8 (-4.7; -26.3)

< 0.001

Total

-

-

-

-10.8 (-7.9; -13.6)

< 0.001

1. *The confidence intervals for differences between CFR in the first wave and successive waves were calculated using the methods of Newcombe et al. ** Significance of differences between the first and successive wave was calculated using the two proportion z-test
2. OR Odds ratio, CI confidence interval
3. Statistically significant differences are indicated in bold