Table 2 Genotype and allele distribution of REST single nucleotide polymorphisms in study participants
· | N | Allele M/m | Genotype n(%) | p | Alleles n(%) | p | |||
|---|---|---|---|---|---|---|---|---|---|
MM | Mm | mm | M | m | |||||
Rs2227902 | G/T | ||||||||
NC | 89 | 81(92.0%) | 5(5.7%) | 2(2.3%) | 0.772 | 167 (94.9%) | 9(5.1%) | 0.849 | |
aMCI | 79 | 71(89.9%) | 7(8.9%) | 1(1.3%) | 149(94.3%) | 9(5.7%) | |||
AD dementia | 84 | 74(88.1%) | 9(10.7%) | 1(1.2%) | 157(93.5%) | 11(6.5%) | |||
Rs3976529 | C/T | ||||||||
NC | 89 | 31(34.8%) | 42(47.2%) | 16(18.0%) | 0.779 | 104(58.4%) | 74(41.6%) | 0.954 | |
aMCI | 79 | 26(33.3%) | 42(53.8%) | 12(12.8%) | 94(58.8%) | 66(41.2%) | |||
AD dementia | 84 | 26(32.5%) | 44(55.0%) | 10(12.5%) | 96(60.0%) | 64(40.0%) | |||