Association of triglyceride glucose index with all-cause and cause-specific mortality among middle age and elderly US population

Table 2 Association of TyG with all-cause and cause specific mortality

All cause and cause specific mortality	Model 1 HR(95% CI)	Model 2 HR(95% CI)	Model 3 HR(95% CI)
All causes
Q1	Ref	Ref	Ref
Q2	1.11 [0.97, 1.27]	0.95 [0.82, 1.09]	0.87 [0.75, 1.00]
Q3	1.11 [0.97, 1.27]	0.98 [0.85, 1.12]	0.84 [0.73, 0.98]*
Q4	1.30 [1.13, 1.48]***	1.25 [1.09, 1.44]**	0.90 [0.77, 1.04]
Continuous	1.18 [1.11, 1.26]***	1.23 [1.14, 1.32]***	1.01 [0.93, 1.10]
Cardiovascular
Q1	Ref	Ref	Ref
Q2	0.69 [0.49, 0.98]*	0.70 [0.50, 0.99]*	0.62 [0.43, 0.88]**
Q3	0.94 [0.68, 1.29]	0.98 [0.71, 1.34]	0.82 [0.59, 1.15]
Q4	1.04 [0.77, 1.41]	1.18 [0.87, 1.61]	0.95 [0.67, 1.35]
Continuous	1.09 [0.93, 1.27]	1.18 [1.01, 1.39]*	1.03 [0.86, 1.25]
Malignant neoplasms
Q1	Ref	Ref	Ref
Q2	1.00 [0.73, 1.36]	1.00 [0.73, 1.36]	1.08 [0.78, 1.49]
Q3	0.89 [0.65, 1.22]	0.92 [0.67, 1.26]	1.05 [0.75, 1.46]
Q4	0.85 [0.62, 1.15]	0.80 [0.59, 1.10]	0.94 [0.66, 1.34]
Continuous	0.88 [0.75, 1.03]	0.84 [0.72, 0.99]*	0.92 [0.76, 1.11]

Model 1 was unadjusted
Model 2 was adjusted for age, gender, and race
Model 3 was adjusted for age, gender, race, education, PIR, BMI, smoker, drinker, physical activity, HBP, DM, CVD, COPD, liver diseases hypoglycemic drug, lipid-lowering drug, LDL, eGFR
^*p < 0.05, ^**p < 0.01, ^***p < 0.001; HR, hazard ratio, CI, confidence interval

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