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Table 4 Associations of PWR and PNR changes with the risk of fatal stroke occurrence in the GBCS (n = 11,038)

From: Association of platelet-to-white blood cell ratio and platelet-to-neutrophil ratio with the risk of fatal stroke occurrence in middle-aged to older Chinese

 

Quartiles of PWR change

Quartiles of PNR change

 

the 1st (≤ -0.11)

the 2nd (−0.11–0.018)

the 3rd (0.018–0.16)

the 4th (≥ 0.16)

the 1st (≤-0.13)

the 2nd (−0.13–0.03)

the 3rd (0.03–0.21)

the 4th (≥0.21)

All stroke

 Model 1 (HR, 95% CI)

1.00

0.74 (0.54–1.02), P = 0.06

0.75 (0.55–1.03), P = 0.07

0.69 (0.50–0.95), P = 0.02

1.00

0.77 (0.57–1.05), P = 0.09

0.63 (0.46–0.88), P = 0.006

0.70 (0.51–0.96), P = 0.03

 Model 2 (HR, 95% CI)

1.00

0.81 (0.59–1.00), P = 0.18

0.85 (0.62–1.16), P = 0.29

0.71 (0.51–0.98), P = 0.03

1.00

0.86 (0.63–1.17), P = 0.34

0.69 (0.50–0.96), P = 0.03

0.73 (0.54–1.01), P = 0.05

P for trend

0.19

0.10

Ischaemic stroke

 Model 1 (HR, 95% CI)

1.00

0.75 (0.48–1.16), P = 0.19

0.72 (0.46–1.12), P = 0.14

0.76 (0.49–1.18), P = 0.23

1.00

0.67 (0.43–1.06), P = 0.08

0.68 (0.44–1.07), P = 0.09

0.82 (0.54–1.25), P = 0.36

 Model 2 (HR, 95% CI)

1.00

0.79 (0.51–1.23), P = 0.30

0.81 (0.52–1.26), P = 0.34

0.78 (0.50–1.20), P = 0.26

1.00

0.74 (0.47–1.17), P = 0.20

0.74 (0.47–1.16), P = 0.19

0.85 (0.56–1.31), P = 0.47

P for trend

0.63

0.50

Haemorrhagic stroke

 Model 1 (HR, 95% CI)

1.00

0.66 (0.35–1.21), P = 0.17

0.89 (0.51–1.55), P = 0.67

0.51 (0.26–0.99), P = 0.04

1.00

0.65 (0.36–1.16), P = 0.15

0.61 (0.34–1.10), P = 0.10

0.44 (0.23–0.85), P = 0.01

 Model 2 (HR, 95% CI)

1.00

0.71 (0.38–1.31), P = 0.27

0.97 (0.55–1.72), P = 0.93

0.48 (0.25–0.95), P = 0.03

1.00

0.72 (0.40–1.28), P = 0.26

0.64 (0.36–1.16), P = 0.14

0.44 (0.23–0.85), P = 0.01

P for trend

0.13

0.09

Unclassified stroke

 Model 1 (HR, 95% CI)

1.00

0.85 (0.44–1.65), P = 0.63

0.63 (0.31–1.31), P = 0.22

0.75 (0.37–1.49), P = 0.41

1.00

1.23 (0.65–2.32), P = 0.53

0.52 (0.23–1.17), P = 0.11

0.80 (0.39–1.63), P = 0.55

 Model 2 (HR, 95% CI)

1.00

0.94 (0.48–1.84), P = 0.86

0.72 (0.35–1.49), P = 0.38

0.77 (0.38–1.55), P = 0.50

1.00

1.36 (0.71–2.60), P = 0.35

0.57 (0.25–1.29), P = 0.18

0.84 (0.41–1.73), P = 0.64

P for trend

0.79

0.16

  1. PWR platelet-to -white blood cell ratio, PNR platelet-to-neutrophil ratio, hs-CRP high-sensitivity C-reactive protein, model 1 a crude hazard ratio model without adjustments, model 2 a multivariate model adjusted for age, sex, diabetes, hypertension, dyslipidaemia, smoking, alcohol consumption, physical activity, body mass index, self-rated health, cancer, genitourinary disease(nephropathy, prostatic disease, and gynecologic diseases) and chest disease(COPD, chronic bronchitis, emphysema, asthma, tuberculosis, and pneumonia), platelet count, and hs-CRP
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BMC Geriatrics

ISSN: 1471-2318

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