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Table 3 Associations of PWR and PNR with the risk of fatal stroke among the participants without CVD at baseline and further hs-CRP adjustment (n = 10,990)

From: Association of platelet-to-white blood cell ratio and platelet-to-neutrophil ratio with the risk of fatal stroke occurrence in middle-aged to older Chinese

  

Quartiles of PWR

 

Quartiles of PNR

 

the 1st (≤ 30)

the 2nd (30.01–36.11)

the 3rd (36.12–43.38)

the 4th (≥ 43.39)

the 1st (≤ 48.64)

the 2nd (48.65–61.11)

the 3rd (61.12–76.25)

the 4th (≥ 76.25)

All stroke

 Model 1 (HR, 95% CI)

1.00

0.83 (0.66–1.06), P = 0.13

0.74 (0.57–0.94), P = 0.02

0.44 (0.32–0.60), P < 0.001

1.00

0.72(0.57–0.91), P = 0.007

0.60 (0.47–0.78), P < 0.001

0.42 (0.31–0.57), P < 0.001

 Model 3 (HR, 95% CI)

1.00

0.98 (0.77–1.25), P = 0.88

0.97 (0.75–1.25), P = 0.82

0.73 (0.53–1.00), P = 0.05

1.00

0.86 (0.68–1.09), P = 0.22

0.83 (0.64–1.08), P = 0.18

0.74 (0.54–1.01),P = 0.06

 P for trend

0.23

0.23

Ischaemic stroke

 Model 1 (HR, 95% CI)

1.00

0.92 (0.66–1.28), P = 0.61

0.77 (0.54–1.10), P = 0.15

0.38 (0.24–0.61), P < 0.001

1.00

0.69 (0.49–0.96), P = 0.03

0.54 (0.37–0.78), P = 0.001

0.38 (0.25–0.59), P < 0.001

 Model 3 (HR, 95% CI)

1.00

1.09 (0.78–1.53), P = 0.60

1.04 (0.72–1.49), P = 0.83

0.66 (0.41–1.08), P = 0.09

1.00

0.82 (0.59–1.15),P = 0.25

0.76 (0.52–1.11),P = 0.15

0.68 (0.43–1.07), P = 0.09

 P for trend

0.22

0.29

Haemorrhagic stroke

 Model 1 (HR, 95% CI)

1.00

0.65 (0.42–1.02), P = 0.06

0.72 (0.46–1.13), P = 0.15

0.52 (0.31–0.87), P = 0.01

1.00

0.65 (0.41–1.03), P = 0.06

0.86 (0.56–1.33), P = 0.50

0.52 (0.31–0.87), P = 0.01

 Model 3 (HR, 95% CI)

1.00

0.75 (0.48–1.18), P = 0.21

0.91 (0.58–1.42), P = 0.67

0.79 (0.46–1.34), P = 0.38

1.00

0.77 (0.48–1.23), P = 0.27

1.16 (0.74–1.81), P = 0.52

0.85 (0.49–1.47), P = 0.56

 P for trend

0.61

0.37

Unclassified stroke

 Model 1 (HR, 95% CI)

1.00

0.90 (0.54–1.52), P = 0.71

0.66 (0.37–1.18), P = 0.16

0.43 (0.22–0.87), P = 0.02

1.00

0.88 (0.54–1.43), P = 0.60

0.38 (0.19–0.73), P = 0.004

0.38 (0.19–0.76), P = 0.006

 Model 3 (HR, 95% CI)

1.00

1.07 (0.64–1.82), P = 0.79

0.90 (0.50–1.62), P = 0.62

0.74 (0.36–1.51), P = 0.41

1.00

1.07 (0.65–1.75), P = 0.80

0.55 (0.28–1.08), P = 0.08

0.71 (0.35–1.44), P = 0.34

  P for trend

0.76

0.21

  1. PWR platelet to white blood cell ratio, PNR platelet to neutrophil ratio, hs-CRP: high sensitivity C-reactive protein, CVD: relative cardiovascular diseases, model 1: a crude hazard ratio model without adjustment for confounders, model 3: a multivariate model adjusted for age, sex, diabetes, hypertension, dyslipidaemia, smoking, alcohol consumption, physical activity, body mass index, self-rated health, cancer, genitourinary disease (nephropathy, prostatic disease, and gynecologic diseases), chest disease (COPD, chronic bronchitis, emphysema, asthma, tuberculosis, and pneumonia), platelet count, and hs-CRP