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Table 1 Baseline characteristics by the PWR and the PNR quartiles of participants in the GBCS (n = 27,796)

From: Association of platelet-to-white blood cell ratio and platelet-to-neutrophil ratio with the risk of fatal stroke occurrence in middle-aged to older Chinese

 

Quartiles of PWR

 

Quartiles of PNR

 

Characteristic

the 1st (≤ 30)

the 2nd (30.01–36.11)

the 3rd (36.12–43.38)

the 4th (≥43.39)

P

the 1st (≤ 48.64)

the 2nd (48.65–61.11)

the 3rd (61.12–76.25)

the 4th

(≥76.25)

P

Number, n

7020

6872

6955

6949

 

6948

6843

6959

6946

 

Age (years)

63.6 ± 7.0

62.5 ± 7.0

61.6 ± 7.0

60.3 ± 6.8

< 0.001

63.8 ± 7.1

62.6 ± 7.1

61.5 ± 7.0

60.1 ± 6.7

< 0.001

Sex, male (%)

3060 (43.6)

2029 (29.5)

1516 (21.8)

1021 (14.7)

< 0.001

3036 (43.7)

2110 (30.4)

1466 (21.1)

1014 (14.6)

< 0.001

Hypertension, n (%)

2257 (32.2)

2039 (29.7)

1908 (27.4)

1609 (23.2)

< 0.001

2298 (33.1)

2037 (29.3)

1932 (27.8)

1546 (22.3)

< 0.001

Diabetes, n (% )

1290 (18.4)

930 (13.5)

844 (12.1)

564 (8.1)

< 0.001

1280 (18.4)

958 (13.8)

822 (11.8)

568 (8.2)

< 0.001

Dyslipidaemia, n (%)

5571 (79.4)

5751 (83.7)

5837 (83.9)

5853 (84.2)

< 0.001

5485 (78.9)

5760 (83.0)

5871 (84.4)

5896 (84.9)

< 0.001

Smoking, n (%)

    

< 0.001

    

< 0.001

 never

4857 (69.2)

5500 (80.0)

5913 (85.0)

6244 (89.8)

 

4780 (68.8)

5543 (79.8)

5946 (85.4)

6245 (89.9)

 

 ever

916 (13.0)

664 (9.7)

558 (8.0)

381 (5.5)

 

942 (13.6)

688 (9.9)

520 (7.5)

369 (5.3)

 

 current

1247 (17.8)

708 (10.3)

484 (7.0)

324 (4.7)

 

1226 (17.6)

712 (10.3)

493 (7.1)

332 (4.8)

 

Alcohol drinking, n (%)

    

< 0.001

    

< 0.001

 never

4772 (68.0)

4836 (70.4)

4965 (71.4)

4955 (71.3)

 

4760 (68.5)

4828 (69.5)

4939 (71.0)

5001 (72.0)

 

 ever

206 (2.9)

168 (2.4)

142 (2.0)

124 (1.8)

 

225 (3.2)

156 (2.2)

127 (1.8)

132 (1.9)

 

 current

2042 (29.1)

1868 (27.2)

1848 (26.6)

1870 (26.9)

 

1963 (28.3)

1959 (28.3)

1893 (27.2)

1813 (26.1)

 

Body mass index, kg/m2

    

< 0.001

    

< 0.001

 <18.5

266 (3.8)

288 (4.2)

302 (4.3)

390 (5.6)

 

285 (4.1)

308 (4.4)

298 (4.3)

355 (5.1)

 

 18.5 – 23.9

3258 (46.4)

3290 (47.9)

3532 (50.8)

3859 (55.6)

 

3320 (47.8)

3272 (47.1)

3480 (50.0)

3867 (55.7)

 

 24 – 27.9

2643 (37.6)

2531 (36.8)

2466 (35.5)

2212 (31.8)

 

2521 (36.3)

2604 (37.5)

2508 (36.0)

2219 (31.9)

 

 ≥28

853 (12.2)

763 (11.1)

655 (9.4)

488 (7.0)

 

822 (11.8)

759 (10.9)

673 (9.7)

505 (7.3)

 

Physical activity, n (%)

    

< 0.001

    

< 0.001

 inactive

555 (7.9)

523 (7.6)

560 (8.1)

617 (8.9)

 

547 (7.9)

522 (7.5)

546 (7.8)

640 (9.2)

 

 moderate

2965 (42.2)

2873 (41.8)

2813 (40.4)

2685 (38.6)

 

2965 (42.7)

2939 (42.3)

2789 (40.1)

2643 (38.1)

 

 active

3500 (49.9)

3476 (50.6)

3582 (51.5)

3647 (52.5)

 

3436 (49.5)

3482 (50.2)

3624 (52.1)

3663 (52.7)

 

Self-rated health, n (%)

5751 (81.9)

5670 (83.0)

5795 (83.3)

5714 (82.2)

0.097

5651 (81.3)

5798 (83.5)

5753 (82.7)

5764 (83.0)

0.006

(good/very good)

     

Cancer, n (%)

123 (1.8)

123 (1.8)

157 (2.3)

136 (2.0)

0.12

109 (1.6)

133 (1.9)

151 (2.2)

146 (2.1)

0.04

GD, n (% )

1735 (24.7)

1770 (25.8)

1915 (27.5)

1982 (28.5)

< 0.001

1702 (24.5)

1832 (26.4)

1882 (27.0)

1986 (28.6)

< 0.001

Chest disease, n (%)

1155 (16.5)

1017 (14.8)

1011 (14.5)

1030 (14.8)

0.006

1123 (16.2)

1027 (14.8)

1027 (14.8)

1036 (14.9)

0.06

WBC, *10^9/L

7.5 ± 1.7

6.6 ± 1.3

6.0 ± 1.6

5.3 ± 1.1

< 0.001

7.6 ± 1.7

6.6 ± 1.2

6.0 ± 1.2

5.2 ± 1.0

< 0.001

NEUT, *10^9/L

4.7 ± 1.5

4.0 ± 1.3

3.6 ± 1.1

3.0 ± 0.9

< 0.001

5.0 ± 1.4

4.0 ± 0.9

3.5 ± 0.8

2.8 ± 0.7

< 0.001

PLT, *10^9/L

185.8 ± 46.3

218.2 ± 42.9

237.5 ± 46.0

268.0 ± 61.0

< 0.001

193.7 ± 50.7

220.8 ± 48.1

236.2 ± 51.1

258.3 ± 60.7

< 0.001

hs-CRP, mg/L

3.8 ± 3.1

3.5 ± 2.8

3.4 ± 2.8

3.3 ± 2.6

< 0.001

4.1 ± 3.2

3.5 ± 2.7

3.4 ± 2.7

3.1 ± 2.6

< 0.001

All stroke

295 (4.2)

215 (3.1)

188 (2.7)

140 (2.0)

< 0.001

315 (4.5)

210 (3.0)

186 (2.7)

127 (1.8)

< 0.001

Ischaemic stroke

146 (2.1)

116 (1.7)

88 (1.3)

63 (0.9)

< 0.001

167 (2.5)

102 (1.5)

83 (1.2)

61 (0.9)

< 0.001

Haemorrhagic stroke

99 (1.5)

58 (0.9)

62 (0.9)

45 (0.7)

< 0.001

95 (1.4)

62 (0.9)

66 (1.0)

41 (0.6)

< 0.001

Unclassified stroke

50 (0.7)

41 (0.6)

38 (0.6)

32 (0.5)

0.22

53 (0.8)

46 (0.7)

37 (0.5)

25 (0.4)

0.009

  1. Hypertension: systolic blood pressure, ≥ 140 mmHg, or diastolic blood pressure, ≤ 90 mmHg, medication and diagnosis; diabetes: fasting blood glucose ≥ 7 mmol/L, medication or diagnosis; dyslipidaemia: total cholesterol ≥ 5.2 mmol/L, triglyceride ≥ 1.7 mmol/L, low density lipoprotein ≥ 3.4 mmol/L, high density lipoprotein < 1.0 mmol/L, medication and diagnosis
  2. WBC white blood cell count, hs-CRP high sensitivity C-reactive protein, NEUT neutrophil, Platelet PLT, PWR platelet to white blood cell ratio, PNR platelet to neutrophil ratio, GD Genitourinary disease (including nephropathy, prostatic disease, and gynecologic diseases), chest disease including COPD, chronic bronchitis, emphysema, asthma, tuberculosis, and pneumonia
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BMC Geriatrics

ISSN: 1471-2318

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