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Table 3 Associations of inflammatory markers with low physical performance

From: Is there an association between inflammatory markers and lower physical performance in older adults?

  Model 1 Model 2 Model 3
OR (95% CI) OR (95% CI) OR (95% CI)
CRP (mg/L)
 1st Tertile (<  1.6) (reference) 1.00   1.00   1.00  
 2nd Tertile (1.6 thru < 5.7) 1.37 (0.81–2.30) 1.38 (0.79–2.42) 1.81 (0.93–3.50)
 3rd Tertile (5.7) 1.83 (1.06–3.12)** 2.16 (1.20–3.90)** 2.23 (1.10–4.55)**
IL-10 (pg/ml)
 1st Tertile (< 1.63) (reference) 1.00   1.00   1.00  
 2nd Tertile (≥1.63 thru < 6.3) 0.92 (0.53–1.57) 0.91 (0.52–1.63) 0.90 (0.46–1.77)
 3rd Tertile (≥6.3) 1.26 (0.72–2.20) 1.24 (0.68–2.24) 1.12 (0.55–2.26)
TNF-α (pg/ml)
 1st Tertile (< 26.0) (reference) 1.00   1.00   1.00  
 2nd Tertile (≥26.0 thru < 38.1) 1.01 (0.59–1.71) 1.15 (0.65–2.03 1.22 (0.63–2.39)
 3rd Tertile (≥38.1) 1.16 (0.66–2.03) 1.19 (0.66–2.17) 1.22 (0.60–2.47)
  1. Model 1: Logistic regression without covariates
  2. Model 2: Additionally adjusted for sex, age, ethnicity background, literacy, alcohol consumption, and smoking habit
  3. Model 3: Additionally adjusted for limitation in ADL, limitation in IADL, presence of hypertension, diabetes, physical activity, and body mass index
  4. **p < 0.05