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Table 4 Comparison of frequently used STOPPFrail-PIM by sex, age, and living condition

From: Prevalence of potentially inappropriate medications based on the STOPPFrail criteria in frail older patients with limited life expectancy: a cross-sectional study

STOPPFrail Criteria Section

Sex

Age

Living Condition

Female

(n = 92)

Male

(n = 79)

p-value

 < 85 years

(n = 105)

 ≥ 85 years

(n = 66)

p-value

Nursing home

(n = 69)

Long-term care hospital

(n = 102)

p-value

n

%

n

n

n

%

n

%

n

%

n

%

A2

Any drug without clear clinical indication

65

70.6

65

82.3

0.76

82

78.1

48

72.7

0.423

50

72.5

80

78.4

0.37

B1

Lipid lowering therapies

32

34.8

30

38.0

0.665

40

38.1

22

33.3

0.528

34

49.3

28

27.5

0.004

D1

Neuroleptic antipsychotics

22

23.9

19

24.1

0.983

25

23.8

16

24.2

0.949

18

26.1

23

22.5

0.595

C1

Antiplatelet for primary prevention

19

20.7

18

22.8

0.736

23

21.9

14

21.2

0.915

22

31.9

15

14.7

0.007

I1

Diabetic oral agents for stringent control

11

12.0

14

17.7

0.453

19

18.1

6

9.1

0.105

9

13.0

16

15.7

0.631

G1

Calcium supplementation

14

15.2

7

8.9

0.207

13

12.4

8

12.1

0.960

9

13.0

12

11.8

0.803

D2

Memantine without BPSD

10

10.9

11

14.0

0.544

13

12.4

8

12.1

0.960

12

17.4

9

8.8

0.094

J1

Multivitamins

7

7.6

6

8.0

0.287

9

8.6

4

6.1

0.105

0

0

13

12.7

-

E2

High-dose H2RA (full therapeutic dose with ≥ 8 weeks)

8

8.7

5

6.3

0.560

8

7.6

5

7.6

0.992

2

2.9

11

10.8

0.056

G4

Long-term oral NSAIDs (≥ 2 months)

7

7.6

6

7.6

0.991

8

7.6

5

7.6

0.992

10

14.5

3

2.9

0.005

  1. STOPPFrail-PIM potentially inappropriate medication according to STOPPFrail (Screening Tool of Older Persons’ Prescriptions in Frail adults with a limited life expectancy) criteria
  2. H2RA H2 receptor antagonist, NSAID non-steroidal anti-inflammatory drug, PPI proton pump inhibitor