Table 1 Available Data in the Santiago Longitudinal Study (29y assessment is ongoing, aiming to relate exposure to early psychosocial adversity to cardiometabolic risk in adulthood)

Epidemiology

Demographics

Age, sex, residence area

X

X

X

X

X

Socioeconomic

Income, economic responsibilities, financial access, human & social capital, future income expectations & worries, SES change.

X

X

X

X

X

Individual risk (I)

Behavior problems, mental health, emotional regulation, stress, dating violence.

X

X

X

X

X

Individual risk (II)

child abuse and neglect, intrafamily violence, having a parent with untreated mental illness, financial distress, feeling unsecure

X

X

X

X

X

Individual risk (III)

Tobacco, alcohol, drug use.

X

X

X

Individual functioning

Work, relationship, living independently, social network, life events.

X

X

Education

Academic record, high school completion, college exams, higher education

X

X

X

Medical history

Acute, chronic, and mental disorders. Records of current and past medication.

X

X

X

Family medical history (I)

T2D, stroke, myocardial infarction, HTA, dyslipidemia

X

X

X

Family medical history (II)

Dementia/Alzheimer’s

X

Diet (I)

Breastfeeding (total and exclusive)

X

Diet (II)

Food-frequency data about food and beverages, 24H recall

X

X

X

Physical activity (I)

Exercise, active commuting, sedentary behavior

X

X

X

Physical activity (II)

Actigraphic recording

X

X

Sleep

Pittsburgh Sleep Quality Index, Munich Chronotype Questionnaire, Epworth Sleepiness Scale

X

X

Clinical

Anthropometry (I)

Height, weight, BMI, BMI (Z score)

X

X

X

X

X

Anthropometry (II)

Waist circumference, WtHR, WHR

X

X

X

Anthropometry (III)

Fat mass, fat-free mass, fat distribution (DXA)

X

X

Cardiometabolic (I)

Blood pressure

X

X

X

Cardiometabolic (II)

Carotid intima thickness, pulse wave velocity.

X

X

Bone density

BMD, BMDz, BMD, T score, BMC (DXA)

X

X

Laboratory

Hematology

Full blood count, hematocrit, hemoglobin, platelets, white cell differentials

X

X

X

X

Liver function

Liver ultrasound, serum AST, ALT, HCV antibody and HBsAg

X

Lipid profile

Total Chol, HDL-Chol, TG, LDL, VLDL

X

X

X

Glucose control

Glucose, insulin, HOMA-IR, HOMA-β, HOMA-S, Disposition Index

X

X

X

Inflammatory markers (I)

hs-CRP

X

X

X

Inflammatory markers (II)

TNFα 

X

Appetite hormones

Leptin, ghrelin, adiponectin, orexin A

X

X

X

Other

Stress hormones

Cortisol (blood, saliva and hair)

X

Bio specimens

Extracted DNA

X

Bio specimens

Blood, biofluids and derivatives

X

X

X

Bio specimens

PBMC

X