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Table 1 Available Data in the Santiago Longitudinal Study (29y assessment is ongoing, aiming to relate exposure to early psychosocial adversity to cardiometabolic risk in adulthood)

From: Multiple events case–control study in a prospective cohort to identify systemic, cellular, and molecular biomarkers of obesity-induced accelerated aging in 30-years-olds: the ObAGE study protocol

  Type of Measure Method/instrument Infancy
assessment
(enrollment to 1y)
Childhood
Assessment
(5,10,12y)
Adolescence
assessment
(16-17y)
23y assessment 29y assessment
Epidemiology Demographics Age, sex, residence area X X X X X
Socioeconomic Income, economic responsibilities, financial access, human & social capital, future income expectations & worries, SES change. X X X X X
Individual risk (I) Behavior problems, mental health, emotional regulation, stress, dating violence. X X X X X
Individual risk (II) child abuse and neglect, intrafamily violence, having a parent with untreated mental illness, financial distress, feeling unsecure X X X X X
Individual risk (III) Tobacco, alcohol, drug use.    X X X
Individual functioning Work, relationship, living independently, social network, life events.     X X
Education Academic record, high school completion, college exams, higher education    X X X
Medical history Acute, chronic, and mental disorders. Records of current and past medication.    X X X
Family medical history (I) T2D, stroke, myocardial infarction, HTA, dyslipidemia    X X X
Family medical history (II) Dementia/Alzheimer’s      X
Diet (I) Breastfeeding (total and exclusive) X     
Diet (II) Food-frequency data about food and beverages, 24H recall    X X X
Physical activity (I) Exercise, active commuting, sedentary behavior    X X X
Physical activity (II) Actigraphic recording    X X  
Sleep Pittsburgh Sleep Quality Index, Munich Chronotype Questionnaire, Epworth Sleepiness Scale    X X  
Clinical Anthropometry (I) Height, weight, BMI, BMI (Z score) X X X X X
Anthropometry (II) Waist circumference, WtHR, WHR    X X X
Anthropometry (III) Fat mass, fat-free mass, fat distribution (DXA)    X X  
Cardiometabolic (I) Blood pressure    X X X
Cardiometabolic (II) Carotid intima thickness, pulse wave velocity.     X X
Bone density BMD, BMDz, BMD, T score, BMC (DXA)    X X  
Laboratory Hematology Full blood count, hematocrit, hemoglobin, platelets, white cell differentials X X X X  
Liver function Liver ultrasound, serum AST, ALT, HCV antibody and HBsAg     X  
Lipid profile Total Chol, HDL-Chol, TG, LDL, VLDL    X X X
Glucose control Glucose, insulin, HOMA-IR, HOMA-β, HOMA-S, Disposition Index    X X X
Inflammatory markers (I) hs-CRP    X X X
Inflammatory markers (II) TNFα     X   
Appetite hormones Leptin, ghrelin, adiponectin, orexin A    X X X
Other Stress hormones Cortisol (blood, saliva and hair)      X
Bio specimens Extracted DNA     X  
Bio specimens Blood, biofluids and derivatives    X X X
Bio specimens PBMC      X