|
Covariates
|
Bivariate models
|
Multiple models
|
|---|
|
HR (95% CI)
|
p-value
|
HR (95% CI)
|
p-value
|
|---|
|
Dementia diagnosis
|
|
No dementia
|
1.36 (1.07; 1.71)
|
0.011
|
1.44 (1.08; 1.92)
|
0.012
|
|
AD
|
1
| |
1
| |
|
VaD
|
0.85 (0.58; 1.25)
|
0.416
|
0.81 (0.55; 1.20)
|
0.293
|
|
AD/VaD
|
0.97 (0.64; 1.47)
|
0.887
|
0.91 (0.60; 1.38)
|
0.648
|
|
FTD
|
1.08 (0.79; 1.48)
|
0.639
|
1.18 (0.86; 1.62)
|
0.305
|
|
DLB/PDD
|
0.92 (0.61; 1.39)
|
0.680
|
0.74 (0.49; 1.13)
|
0.168
|
|
Unspecified dementia
|
1.79 (1.19; 2.70)
|
0.005
|
1.76 (1.17; 2.67)
|
0.007
|
|
Patient characteristics
|
|
Age at admission
|
1.03 (1.02; 1.05)
|
<0.001
|
1.04 (1.03; 1.05)
|
<0.001
|
|
Gender, male
|
1.24 (1.05; 1.47)
|
0.014
|
1.32 (1.10; 1.58)
|
0.003
|
|
Lived alone before admission, no
|
1.12 (0.94; 1.34)
|
0.202
|
1.09 (0.90; 1.33)
|
0.360
|
|
Time dependent variables
|
|
GMHR, good or excellent
|
0.64 (0.54; 0.76)
|
<0.001
|
0.80 (0.67; 0.96)
|
0.018
|
|
PSMS
|
1.10 (1.08; 1.12)
|
<0.001
|
1.10 (1.08; 1.13)
|
<0.001
|
|
NPI-AGI
|
1.00 (0.99; 1.01)
|
0.905
|
0.99 (0.97; 1.00)
|
0.056
|
|
NPI- PSY
|
1.02 (1.00; 1.04)
|
0.142
|
1.02 (1.00; 1.04)
|
0.234
|
|
NPI-AFF
|
1.02 (1.00; 1.03)
|
0.026
|
1.02 (1.00; 1.04)
|
0.022
|
|
CDR-SoB
|
1.03 (1.01; 1.06)
|
0.002
|
1.00 (0.97; 1.03)
|
0.891
|
- HR Hazard ratio, CI Confidence interval, AD Alzheimer’s disease, VaD vascular dementia, FTD frontotemporal dementia, DLB dementia with Lewy bodies, PD Parkinson’s disease dementia, GMHR General medical health rating, PSMS Physical self-maintenance scale, NPI Neuropsychiatric inventory, NPI-AGI NPI sub-syndromes agitation/aggression, disinhibition and irritability, NPI-PSY NPI sub-syndromes delusions and hallucinations, NPI-AFF NPI sub-syndromes depression and anxiety, CDR-SoB Clinical dementia rating scale – sum of boxes, CI Confidence interval
