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Table 3 Logistic regression analyses of the interaction between ω-6 fatty acids intake and blood cadmium on low cognitive performance

From: Interaction between ω-6 fatty acids intake and blood cadmium on the risk of low cognitive performance in older adults from National Health and Nutrition Examination Survey (NHANES) 2011–2014

Total fatty acids intake Blood cadmium Model 1 Model 2 Model 3
OR (95%CI) P OR (95%CI) P OR (95%CI) P
ω-6 fatty acids        
Normal-level Normal-level Ref   Ref   Ref  
Normal-level High-level 2.069 (1.535–2.788) < 0.001 1.955 (1.466–2.605) < 0.001 1.484 (1.083–2.037) 0.011
Low-level Normal-level 1.666 (1.149–2.414) 0.005 1.637 (1.124–2.383) 0.012 1.548 (1.005–2.386) 0.039
Low-level High-level 3.403 (1.814–6.384) < 0.001 3.237 (1.743–6.011) < 0.001 2.602 (1.310–5.169) 0.005
RERI (95%CI) 0.668 (0.240–1.096) 0.654 (0.248–1.060) 0.570 (0.208–0.932)
AP (95%CI) 0.196 (0.089–0.304) 0.202 (0.095–0.309) 0.219 (0.102–0.336)
S (95%CI) 1.385 (1.137–1.687) 1.413 (1.154–1.730) 1.552 (1.189–2.027)
  1. OR odds ratio, CI confidence interval, Ref reference, RERI relative excess risk due to interaction, AP attributable proportion of interaction, S synergy index
  2. Model 1: Univariable logistic regression analysis
  3. Model 2: Multivariate logistic regression analysis with adjustment for age, gender and BMI
  4. Model 3: Multivariate logistic regression analysis with adjustment for age, gender, BMI, race, marital status, educational level, annual household income, drinking, work activity, recreational activities, depression, hypertension, diabetes, stroke, CHF, heart attack, TC, GHb, 25(OH)D