Skip to main content

Table 2 Adjusted HRs (95% CI) for the association of baseline (1991–1993) hs-cTnT and NT-proBNP with incident frailty

From: Subclinical cardiovascular disease and frailty risk: the atherosclerosis risk in communities study

Variable Hs-CTnT
(≥14 vs. < 14 ng/L)
NT-proBNP
(≥100 vs. < 100 pg/mL)
NT-proBNP
(≥300 vs. < 300 pg/mL)
HR (95% CI) P HR (95% CI) P HR (95% CI) P
Unadjusted 2.569 (1.532–4.310) < 0.001 1.903 (1.518–2.386) < 0.001 2.676 (1.505–4.760) < 0.001
Model 1 2.156 (1.254–3.708) 0.005 1.643 (1.282–2.105) < 0.001 2.233 (1.244–4.011) 0.007
Model 2 2.127 (1.129–4.010) 0.020 1.330 (1.007–1.756) 0.045 2.614 (1.283–5.327) 0.008
  1. Model 1: adjusted by age, sex, center-race, education (<high school, high school, or > high school), smoking (never, former, current), drinking (never, former, current), body mass index, systolic blood pressure, heart rate, total cholesterol, triglycerides
  2. Model 2: adjusted by model 1 plus cognition Z score, hypertension, diabetes, and cancer
  3. hs-CTnT high-sensitive cardiac troponin T, NT-proBNP N-terminal pro-B-type natriuretic peptide, HR hazard ratio, CI confidence interval