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Table 1 Characteristics of the study participants based on the severity of sarcopenia in the BEH program

From: Association between platelet, white blood cell count, platelet to white blood cell ratio and sarcopenia in community-dwelling older adults: focus on Bushehr Elderly Health (BEH) program

  Parameters Total
(n = 2368)
   Severe sarcopenia
(n = 454)
p-value a
No sarcopenia
(n = 1522)
Mild sarcopenia
(n = 392)
Demographic & Clinical Age (years) 69.30 ± 6.33 67.99 ± 5.48 69.58 ± 6.05 73.44 ± 7.35 < 0.0001
Sex (Female), n (%) 1223 (51.65) 836 (54.93) 132 (33.67) 255 (56.17) < 0.001
Marital status, n (%) Single 19 (0.80) 10 (0.66) 2 (0.51) 7 (1.54) < 0.001
Married 1824 (77.03) 1189 (78.12) 331 (84.44) 304 (66.96)
Divorce 20 (0.84) 10 (0.66) 6 (1.53) 4 (0.88)
Widow 505 (21.33) 313 (20.57) 53 (13.52) 139 (30.62)
Smoking None 1523 (83.41) 994 (83.95) 233 (76.90) 296 (87.32) 0.003
Yes, occasionally 30 (1.64) 15 (1.27) 10 (3.30) 5 (1.47)
Yes, regularly 273 (14.95) 175 (14.78) 60 (19.80) 38 (11.21)
Cognitive disorder, n (%) 1397 (59.45) 860 (57.03) 212 (54.36) 325 (71.90) < 0.001
Metabolic syndrome, n (%) 1179 (49.81) 863 (56.70) 127 (32.40) 189 (41.72) < 0.001
Chronic disease None 244 (10.30) 152 (9.99) 55 (14.03) 37 (8.15) 0.066
One 317 (13.39) 199 (13.07) 53 (13.52) 65 (14.32)
Two or more 1807 (76.31) 1171 (76.94) 284 (72.45) 352 (77.53)
SBP (mm Hg) 139.57 ± 19.32 140.08 ± 18.83 136.44 ± 20.16 140.57 ± 19.98 0.0019
DBP (mm Hg) 81.49 ± 8.64 82.10 ± 8.40 80.48 ± 8.74 80.29 ± 9.15 < 0.0001
BMI (kg/m2) 27.33 ± 4.63 29.05 ± 4.44 24.19 ± 3.07 24.28 ± 3.16 < 0.0001
Waist circumference (cm) 98.39 ± 11.67 101.81 ± 10.98 92.33 ± 10.13 92.16 ± 10.42 < 0.0001
WHR .89 ± .12 .90 ± .15 .89 ± .06 .88 ± .07 0.1193
IADL (dependent), n (%) 1201 (56.31) 751 (53.84) 164 46.99) 286 (73.52) < 0.001
Sarcopenia parameters ASM (kg) 15.89 ± 3.63 16.77 ± 3.52 15.24 ± 3.13 13.51 ± 3.15 < 0.0001
SMI (kg/m2) 6.23 ± .98 6.58 ± .90 5.78 ± .77 5.45 ± .76 < 0.0001
Total body fat mass (%) 37.57 ± 8.11 38.71 ± 8.11 34.00 ± 7.58 36.83 ± 7.57 < 0.0001
Gait speed (m/s) .84 ± .30 .87 ± .31 1.05 ± .17 .59 ± .17 < 0.0001
SPPB 9.38 ± 1.73 9.62 ± 1.72 9.61 ± 1.04 8.22 ± 1.86 < 0.0001
Mean hand grip (kg) 22.22 ± 9.20 23.83 ± 9.64 22.17 ± 7.61 16.88 ± 6.59 < 0.0001
Medications Anti-inflammatory medication, n (%) 1171 (60.27) 771 (60.71) 157 (53.22) 243 (64.29) 0.012
AntiPLT medication, n (%) 995 (51.21) 661 (52.05) 137 (46.44) 197 (52.12) 0.205
Antihyperlipidemia medication, n (%) 807 (41.53) 563 (44.33) 111 (37.63) 133 (35.19) 0.002
Anti-HTN medication, n (%) 1186 (61.04) 794 (62.52) 153 (51.86) 239 (63.23) 0.002
DM medication, n (%) 591 (30.42) 390 (30.71) 83 (28.14) 118 (31.22) 0.641
Biochemical parameters Total cholesterol 182.13 ± 44.20 182.54 ± 44.14 181.38 ± 44.38 181.39 ± 44.33 0.8301
HDL-cholesterol (mg/dl) 45.96 ± 11.20 45.67 ± 10.95 45.90 ± 10.99 46.99 ± 12.16 0.0873
LDL- cholesterol 109.40 ± 37.75 109.07 ± 38.39 110.28 ± 36.88 109.74 ± 36.38 0.8340
TG 135.69 ± 70.27 140.45 ± 69.57 127.92 ± 63.16 126.45 ± 76.77 0.0001
Hgb 14.50 ± 1.73 14.56 ± 1.72 14.57 ± 1.65 14.21 ± 1.84 0.0004
RBC (10^6) 5.01 ± .63 5.03 ± .62 5.03 ± .62 4.91 ± .69 0.0017
PLT (10^3) 262.52 ± 66.02 262.10 ± 65.23 256.61 ± 67.75 269.02 ± 66.75 0.0224
WBC (10^3) 7.36 ± 2.19 7.43 ± 2.36 7.16 ± 1.82 7.30 ± 1.84 0.0789
PLT to WBC ratio 37.28 ± 11.34 36.94 ± 11.16 37.22 ± 11.18 38.48 ± 11.99 0.0402
BUN 14.98 ± 5.70 14.59 ± 5.42 15.26 ± 5.31 16.07 ± 6.73 < 0.0001
Creatinine 1.10 ± .36 1.08 ± .35 1.12 ± .31 1.13 ± .44 0.0292
Uric acid 5.17 ± 1.30 5.21 ± 1.28 5.14 ± 1.26 5.08 ± 1.39 0.1882
Alk-P 220.32 ± 75.80 222.23 ± 77.74 212.07 ± 74.28 221.05 ± 69.98 0.0593
HbA1c 5.67 ± 1.56 5.69 ± 1.54 5.57 ± 1.47 5.66 ± 1.67 0.3843
  1. BEH Bushehr elderly health, SBP Systolic blood pressure, DBP diastolic blood pressure, BMI Body mass index, WHR waist to hip ratio, IADL Instrumental activities of daily living, ASM Appendicular skeletal muscle mass, SMI skeletal muscle mass index, SPPB Short Physical Performance Battery, HTN Hypertension, HDL high-density lipoproteins, LDL low-density lipoproteins, TG triglycerides, Hgb Hemoglobin, RBC Red blood cells, PLT platelet, WBC White blood cells, PWR PLT to WBC ratio, BUN blood urea nitrogen, ALK-P Alkaline phosphatase, HbA1c hemoglobin A1c
  2. a P-values for continuous variables and categorical variables were assessed using ANOVA and Chi-square, respectively