Specific lysophosphatidylcholine and acylcarnitine related to sarcopenia and its components in older men

BMC Geriatrics

Table 3 Liner regression analysis for associations of serum metabolites with muscle parameters

variables	Handgrip strength			Gait speed			SMI
variables	β	SE	P	β	SE	P	β	SE	P
Valine	-0.030	0.062	0.627	-0.001	0.004	0.767	-0.009	0.015	0.526
Ileucine	-0.088	0.168	0.599	-0.001	0.011	0.929	-0.010	0.040	0.807
Leucine	0.0125	0.098	0.898	0.002	0.007	0.706	-0.003	0.023	0.897
Tyrosine	0.1364	0.130	0.294	0.005	0.009	0.598	-0.033	0.0318	0.280
Tryptophan	0.362	0.132	0.007	0.016	0.009	0.069	-0.021	0.032	0.509
Glutamine	0.009	0.056	0.876	-0.002	0.003	0.675	-0.013	0.013	0.316
Glutamate	0.041	0.079	0.604	0.010	0.005	0.049	0.004	0.019	0.832
Glycine	-0.039	0.019	0.043	-0.002	0.001	0.156	-0.006	0.005	0.171
Gln/Glu	-0.555	0.852	0.516	-0.091	0.057	0.113	-0.156	0.202	0.441
BCAA	-0.011	0.033	0.751	-0.000	0.002	0.962	-0.003	0.008	0.668
C2	-0.473	0.547	0.388	-0.070	0.037	0.058	-0.047	0.129	0.714
C5	18.866	46.553	0.686	1.126	3.140	0.720	15.414	10.965	0.161
C8	-14.478	8.900	0.105	-0.400	0.603	0.508	0.437	2.116	0.837
C10	-12.446	7.014	0.077	-0.434	0.475	0.363	0.045	1.669	0.979
C12	-61.396	29.987	0.042	-4.337	2.021	0.033	-1.499	7.151	0.834
C14	-228.4	92.431	0.014	-16.739	6.219	0.008	-19.489	22.096	0.379
C16	-8.973	32.181	0.781	-2.307	2.166	0.288	-1.484	7.609	0.846
LPC16:0	0.003	0.013	0.818	0.002	0.001	0.080	0.006	0.003	0.044
LPC18:2	0.061	0.036	0.090	0.004	0.002	0.131	0.012	0.008	0.148

Adjusted variables: Age, BMI, smoking, alcohol drinking, physical activity, malnutrition, polypharmacy, comorbidities
Abbreviates: SMI skeletal muscle index, Glu glutamate, Gln glutamine, BCAA branched-chain-amino acids, C2 acetylcarnitine, C5:valeryl-L-carnitine,C8:octanoyl-L-carnitine,C10:decanoyl-L-carnitin,C12:dodecanoy-L-carnitine,C14:tetradecanoyl-L-car-nitine,C16:hexadec-C16anoyl-L-carnitine, LPC16:0:1-palmitoyl-2-hydroxy-sn-glycero-3-phosphocholine, LPC18:2: 1-linoleoyl-2-hydroxy-sn-glycero-3-phosphocholine

ISSN: 1471-2318