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Table 1 Characteristics of the study population, overall and by use of a statin. Mean (SD) if not otherwise indicated

From: Association between statin use and physical performance in home-dwelling older patients receiving polypharmacy: cross-sectional study

 

Overall

N = 174

Non-users

N = 87

Users

N = 87

Mean difference (95% CI)a

Age (years)

83.3 (7.3)

85.7 (7.5)

81.0 (6.4)

−4.7 (−6.8 to − 2.6)

Female, n (%)

118 (67.8)

70 (80.5)

48 (55.2)

p < 0.01b

BMI (kg/m2)

25.2 (5.6)c

24.2 (5.4)

26.3 (5.6)

2.1 (0.4 to 3.8)

CIRS (0-56)

16.7 (4.3)

16.3 (4.3)

17.1 (4.2)

0.9 (−0.4 to 2.1)

FIM (18-126)

111.1 (10.8)

110.6 (10.4)

111.7 (11.1)

1.1 (−2.1 to 4.4)

CDR (0-18)

2.3 (3.3)

2.5 (3.3)

2.2 (3.4)

−0.3 (−1.3 to 0.7)

Grip strength (kg)

18.5 (8.1)

15.7 (6.8)

21.4 (8.3)

5.7 (3.4 to 8.0)

Grip strength indicating sarcopenia d, n (%)

105 (60)

61 (70)

44 (51)

p = 0.01b

SPPB (0-12)

4.6 (3.1)

4.4 (3.0)

4.8 (3.2)

0.4 (−0.6 to 1.3)

SPPB ≤8, n (%)

149 (86)

74 (85)

75 (86)

p = 0.8b

Gait speed (m/s)

0.62 (0.20)e

0.59 (0.21)

0.64 (0.19)

0.06 (−0.01 to 0.11)

Gait speed ≤0.8 m/s, n (%)

128 (79)e

68 (83)

60 (75)

p = 0.2b

SPPB subscore balance (0-4)

1.6 (1.3)

1.6 (1.3)

1.7 (1.4)

0.1 (−0.3 to 0.5)

SPPB subscore chair stand (0-4)

0.8 (1.2)

0.8 (1.2)

0.8 (1.2)

0.0 (−0.3 to 0.4)

n (% of 87) using statin as secondary prevention

  

64 (74)

 
  1. aNon-users are reference category
  2. bChi square test
  3. cn = 168. Six (four statin users) missing due to height not reported
  4. d < 27 kg for men, < 16 kg for women
  5. en = 162. Twelve (seven statin users) missing due to amputation or hemiparesis
  6. CI Confidence Interval, BMI Body mass Index, CIRS Cumulative Illness Rating Scale, FIM Functional Independence Measure, CDR Clinical Dementia Rating Scale (Sum of Boxes), SPPB Short Physical Performance Battery