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Table 5 Comparison of breast cancer-specific survival (BCSS) and overall survival (OS) between matched patients with chemotherapy and no-chemotherapy in specific clinical variables

From: The impact of chemotherapy and survival prediction by machine learning in early Elderly Triple Negative Breast Cancer (eTNBC): a population based study from the SEER database

Variables

BCSS

OS

Events No

HRs (95%CI)

Pa

Events No

HRs (95%CI)

Pa

T1N1M0 (n = 109)

21

 

0.666

34

 

0.872

 Chemotherapy

 

0.778(0.249–2.432)

  

1.072(0.458–2.508)

 

 No-Chemotherapy

 

Reference

  

Reference

 

T2N0M0 (n = 595)

80

 

 < 0.001

123

 

 < 0.001

 Chemotherapy

 

0.420(0.261–0.675)

  

0.361(0.243–0.536)

 

 No-Chemotherapy

 

Reference

  

Reference

 

Stage IIb (n = 283)

63

 

0.321

90

 

0.039

 Chemotherapy

 

0.767(0.454–1.296)*

  

0.640(0.419–0.978)

 

 No-Chemotherapy

 

Reference

  

Reference

 

Grade I&II (n = 546)

53

 

0.387

81

 

0.306

 Chemotherapy

 

0.781(0.445–1.368)

  

0.790(0.503–1.240)*

 

 No-Chemotherapy

 

Reference

  

Reference

 

Grade III (n = 2,114)

306

 

 < 0.001

461

 

 < 0.001

 Chemotherapy

 

0.559(0.441–0.708)*

  

0.505(0.415–0.615)*

 

 No-Chemotherapy

 

Reference

  

Reference

 
  1. Abbreviation: HR Hazard ratio, CI Confidence interval, BCSS Breast cancer-specific survival, OS Overall survival, Events No Number of events
  2. aP value was adjusted by a multivariate Cox proportional hazard regression model or a time-dependent covariate analysis. Bold type indicates significance
  3. bThe groups using time-dependent covariate analysis were specifically marked with asterisks(*)