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Table 2 Multivariate Cox proportional hazard model of breast cancer-specific survival (BCSS) and overall survival (OS) in all patients

From: The impact of chemotherapy and survival prediction by machine learning in early Elderly Triple Negative Breast Cancer (eTNBC): a population based study from the SEER database

Variables

BCSS

OS

HR (95% CI)

P

HR (95% CI)

P

Age (years)

70–79

Reference

 

Reference

 

80 + 

1.315(1.111–1.557)

0.001

1.629(1.429–1.856)

 < 0.001

Marital status

Married

Reference

 

Reference

 

Not marrieda

1.062(0.902–1.250)

0.472

1.120 (0.985–1.272)

0.084

Race

White

Reference

 

Reference

 

Black

1.068 (0.875–1.305)

0.516

1.070 (0.914–1.252)

0.399

Otherb

0.706 (0.507–0.983)

0.039

0.709 (0.549–0.916)

0.008

Grade

I and II

Reference

 

Reference

 

III

1.510 (1.222–1.865)

 < 0.001

1.344(1.152–1.568)

 < 0.001

Stage

I

Reference

 

Reference

 

II

3.982 (3.137–5.055)

 < 0.001

2.602(2.221–3.048)

 < 0.001

III

11.609(9.015–14.949)

 < 0.001

6.528(5.468–7.793)

 < 0.001

Surgery approach

No surgery

Reference

 

Reference

 
 

Mastectomy and BCS

0.246(0.198–0.304)

 < 0.001

0.293(0.245–0.351)

 < 0.001

Radiation

No

Reference

 

Reference

 

Yes

0.626 (0.529–0.741)

 < 0.001

0.565 (0.495–0.645)

 < 0.001

Chemotherapy

No

Reference

 

Reference

 

Yes

0.656 (0.553–0.779)

 < 0.001

0.561(0.488–0.644)

 < 0.001

  1. Abbreviation: 70–79 70–79 years old, 80 + More than 80 years old, BCS Breast Conserving Surgery, HR Hazard ratio
  2. aNot married includes divorced, separated, single (never married), unmarried or domestic partner, and widowed
  3. bOther includes American Indian/Alaskan native and Asian/Pacific Islander and Unknown. Bold type indicates significance