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Table 3 Studies reporting the relationship between frailty and thirty-day mortality patients undergoing surgery for colorectal cancer

From: The prevalence and prognostic value of frailty screening measures in patients undergoing surgery for colorectal cancer: observations from a systematic review

Study Design Patient (n =) Country Frailty screening tool Frailty Prevalence Timing of assessment Age (Median/ Mean; years) % Male/Female TNM Stage Comments
Artiles-Armas et al. (2021,) [34] Prospective 149 Spain Clinical Frailty Scale 42 (CSHA CFS ≥ 4) Pre-operative 75 64/36 I-IV Frailty associated with increased mortality on UV analysis
(P = 0.009)
Miller et al. (2020,) [26] Retrospective 9,252 USA Modified Frailty Index (MFI-5) 15 (MFI ≥ 2) Pre-operative NR (25% ≥ 65) 58/42 I-IV Frailty associated with increased mortality on MV binary log regression
(OR 20.8, 95% CI 6.2–70.0, P < 0.001)
Reisinger et al. (2015,) [28] Retrospective 340 Netherlands Groningen Frailty Indicator 25 (GFI ≥ 5) Pre-operative 69 50/50 II-IV Frailty not associated with increased mortality on UV binary log regression
(P = 0.72)
Souwer et al. (2018,) [30] Retrospective 139 Netherlands Geriatric 8 questionnaire 50 (G8 ≤ 14) Pre-operative 77.8 55/45 I-III Frailty not associated with increased mortality on UV binary log regression
(P = 1.00)
  1. UV Univariate, MV Multivariate, OR Odds Ratio