Table 7 Associations between patient-related parameters and psychotropic drug treatment If value 1 is not included in the 95% confidence interval, a significant association is indicated (p < 0.05); these results are printed in bold. 95% Confidence interval (lower boundary, upper boundary)
From: A bitter pill to swallow - Polypharmacy and psychotropic treatment in people with advanced dementia
Parameters | Antipsychotics (N05A) OR (CI 95%) | Antidepressants (N06A) OR (CI 95%) | Sedatives (=antipsychotic + anxiolytic + hypnotic drugs) OR (CI 95%) | Pain medication (=N02A+N02B) OR (CI 95%) | |
|---|---|---|---|---|---|
Sex | male | 0.97 (0.51-1.85) | 0.86 (0.45-1.67) | 0.94 (0.51-1.75) | 0.49 (0.19-1.22) |
female | Reference | ||||
Place of living | LTC | 1.94 (0.96-3.93) | 0.94 (0.47-1.90) | 1.63 (0.83-3.18) | 3.32 (1.18-9.37) |
HC | Reference | ||||
Dementia onset | LOD | 1.01 (0.37-2.82) | 1.07 (0.37-3.08) | 0.74 (0.28-1.98) | 0.81 (0.21-3.14) |
YOD | Reference | ||||
Dementia etiology | FTLD | 0.35 (0.15-0.83) | 1.15 (0.52-2.54) | 0.38 (0.17-0.86) | 0.98 (0.33-2.22) |
Others | 1.01 (0.35-2.90) | 2.91 (1.04-8.16) | 1.23 (0.45-3.39) | 0.34 (0.06-1.89) | |
AD | Reference | ||||
CDR (sum of boxes) | 1.28 (0.87-1.88) | 0.72 (0.51-1.03) | 1.08 (0.76-1.53) | 1.14 (0.60-2.18) | |
QUALID | 1.03 (0.97-1.10) | 1.03 (0.97-1.10) | 1.04 (0.97-1.10) | 1.02 (0.93-1.11) | |
PAINAD | 1.04 (0.85-1.27) | 0.96 (0.79-1.17) | 0.99 (0.82-1.20) | 1.25 (0.98-1.60) | |
Barthel-Index | 1.01 (0.99-1.02) | 1.00 (0.98-1.02) | 1.00 (0.98-1.02) | 0.99 (0.96-1.01) | |
NPI total | 1.04 (1.01-1.07) | 0.99 (0.96-1.01) | 1.04 (1.01-1.07) | 0.98 (0.95-1,02) | |
EOLD SM total | 1.02 (0.97-1.07) | 0.94 (0.89-1.00) | 1.04 (0.99-1.09) | 0.99 (0.92-1.06) | |
Age* | 0.78 (0.49-1.25) | 0.68 (0.41-1.11) | 0.84 (0.53-1.32) | 1.21 (0.64-2.29) |