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Table 1 Demographics and neuropsychological tests for NC, SCD, aMCI

From: Differential associations of visual memory with hippocampal subfields in subjective cognitive decline and amnestic mild cognitive impairment

Index

NC

n = 51

SCD

n = 47

aMCI

n = 62

Test statictics

p value

Age (y)

67.98 ± 5.01

66.81 ± 4.67

68.76 ± 4.81

2.173

0.117

Education (y)

12.65 ± 2.91

11.83 ± 2.19

11.61 ± 2.70

2.334

0.100

Sex (% Female)

27 (52.9)

34 (72.3)

33 (53.2)

5.073

0.079

APOE (% ε4)

7 (13.7)

10 (21.3) *

25 (40.3) **†

11.075

0.004

General Cognition

 MMSE (range 24–30)

28.61 ± 1.29

27.93 ± 1.41

26.13 ± 1.53**†

46.336

 < 0.001

 MoCA-B (range 18–30)

27.06 ± 1.33

25.83 ± 2.11*

22.77 ± 2.57**†

75.078

 < 0.001

 ACE-III (range 60–97)

87.57 ± 4.12

81.19 ± 5.38 **

73.50 ± 6.03**†

99.939

 < 0.001

Language Function

 AFT (range 9–29)

19.26 ± 3.50

17.34 ± 4.29*

14.55 ± 3.62**†

22.046

 < 0.001

 BNT (range 17–30)

25.67 ± 2.61

25.06 ± 2.69

22.82 ± 3.21**†

15.492

 < 0.001

Attention/Executive Function

 STT-A (range 21–140)

45.02 ± 14.46

51.02 ± 14.24

56.39 ± 19.13**

17.344

0.002

 STT-B (range 21–238)

118.55 ± 28.03

117.6 ± 27.85

147.05 ± 38.35**†

20.993

 < 0.001

 SDMT (range 13–68)

42.28 ± 8.63

36.79 ± 9.03*

30.97 ± 10.37**†

20.103

 < 0.001

Veral Memory

 AVLT-IR (range 5–29)

19.29 ± 4.16

17.38 ± 4.44

12.16 ± 2.89**†

70.266

 < 0.001

 AVLT-DR (range 0–12)

6.16 ± 2.19

5.11 ± 1.97*

1.73 ± 1.37**†

90.483

 < 0.001

 AVLT-Re (range 11–24)

22.18 ± 1.32

21.45 ± 2.24

17.81 ± 2.35**†

82.978

 < 0.001

Visual Memory

 BVMT-R IR (range 2–36)

21.92 ± 7.08

18.34 ± 7.00*

15.24 ± 6.17**

13.842

 < 0.001

 PLT-DR (range 0–12)

7.86 ± 1.84

6.81 ± 2.14*

5.61 ± 2.31**†

15.868

 < 0.001

 DMSPCAD (range 27–100)

79.10 ± 12.81

77.17 ± 16.85

69.65 ± 16.68**†

5.857

0.004

 PALFAMS (range 2–18)

10.69 ± 3.41

8.51 ± 3.64*

7.95 ± 3.72**

8.654

 < 0.001

  1. Note: Sex and APOE ε4 status are represented as number (percent), other data are represented as mean ± standard deviation
  2. NC Normal control, SCD Subjective cognitive decline, aMCI amnestic mild cognitive impairment, MMSE Chinese Version of the Mini-Mental State Examination, MoCA-B Chinese version of the Montreal Cognitive Assessment Basic, ACE-III Addenbrooke’s Cognitive Examination III, AFT Animal Verbal Fluency Test, BNT Boston Naming Test, STT Shape Trail Test, SDMT Symbol Digit Modalities Test, AVLT Auditory Verbal Learning Test, IR Immediate Recall, DR Delayed Recall, Re Recognition, BVMT-R Brief Visuospatial Memory Test-Revised, PLT Pictorial Learning Test, DMSPCAD Delayed Matching to Sample Percent Correct (all delays), PALFAMS Paired Associates Learning First Attempt Memory Score
  3. * compared with NC group, p < 0.05;** compared with NC group, p < 0.01; † compared with SCD group, p < 0.05