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Table 4 Patients’ characteristics by AGU

From: Current practice in benzodiazepine receptor agonists deprescribing on acute geriatric wards: a cohort study

 

AGU 1

(n= 172)

AGU 2

(n= 215)

AGU 3

(n= 174)

Demographic data

 Age (years): mean; SD

86.7; 5.6

84.4; 5.7

85.1; 6.2

 Female

123 (71.5%)

143 (66.5%)

126 (72.4%)

Comorbidities

 CIRS-G: median; Q1-Q3

20; 17-23

24; 20-28

20.5; 17-24.75

 Anxiety

10 (5.8%)

59 (27.4%)

23 (13.2%)

 Sleep disorder

5 (2.9%)

26 (12.1%)

18 (10.3%)

 Restless leg syndrome

1 (0.6%)

11 (5.1%)

4 (2.3%)

 Depression

33 (19.2%)

63 (29.3%)

53 (30.5%)

 Extrapyramidal syndrome

13 (7.6%)

25 (11.6%)

20 (11.5%)

 COPD

23 (13.4%)

34 (15.8%)

25 (14.4%)

 Cognitive decline

129 (75.0%)

83 (38.6%)

104 (59.8%)

 Delirium

55 (32.0%)

76 (35.3%)

57 (32.8%)

 Fall at admission

77 (44.8%)

112 (52.1%)

85 (48.9%)

 Current fracture

22 (12.8%)

30 (14.0%)

33 (19.0%)

 Previous fracture

60 (34.9%)

83 (38.6%)

58 (33.3%)

 Psychiatric disorder

3 (1.7%)

5 (2.3%)

8 (4.6%)

Administrative data

Place of residence:

 Home

122 (70.9%)

169 (78.6%)

121 (69.5%)

 Nursing home

50 (29.1%)

46 (21.4%)

53 (30.5%)

Length of stay (days): median; Q1-Q3

15; 11.75-20

15; 11-21.5

16; 11-26

Admission route:

   

 Emergency

146 (84.9%)

116 (54.0%)

124 (71.3%)

 Direct

15 (8.7%)

70 (32.6%)

25 (14.4%)

 Transfer

11 (6.4%)

29 (13.5%)

25 (14.4%)

Discharge destination:

 Home

88 (51.2%)

108 (50.2%)

81 (46.6%)

 Nursing home

61 (35.5%)

68 (31.6%)

71 (40.8%)

 Another ward

23 (13.4%)

39 (18.1%)

22 (12.6)

Medications at admission

 Total medications: median; Q1-Q3

8.5; 6-10.25

10; 8-13

8; 6-11

 Polypharmacy

149 (86.6%)

206 (95.8%)

159 (91.4%)

 Excessive polypharmacy

63 (36.6%)

122 (56.7%)

65 (37.4%)

 BZRA dose: median; Q1-Q3

1.3; 1-2.5

1; 0.95-2

1; 0.85-2

 Multi-BZRA users

29 (16.9%)

51 (23.7%)

32 (1.8%)

 Psychotropic drug users

119 (69.2%)

157 (73.0%)

123 (70.7%)

 Psychotropic polypharmacy

69 (40.1%)

97 (45.1%)

65 (37.4%)

 Antipsychotic users

39 (22.7%)

43 (20.0%)

34 (19.5%)

 Antidepressant users

76 (44.2%)

118 (54.9%)

79 (45.4%)

 Trazodone users

13 (7.6%)

30 (14.0%)

16 (9.2%)

Miscellaneous

 Palliative status

10 (5.8%)

8 (3.7%)

24 (13.8%)

 Intervention of a clinical pharmacist

0 (0.0%)

202 (94.0%)

0 (0.0%)

 Identification of a BZRA-related adverse event by the treating physician

11 (6.4%)

51 (23.7%)

26 (14.9%)

 BZRA switch between admission and discharge

11 (6.4%)

22 (10.2%)

32 (18.4%)

  1. SD standard deviation, Q1 first quartile, Q3 third quartile, CIRS-G Cumulative Illness Rating Scale-Geriatric, COPD Chronic Obstructive Pulmonary Disease, AGU acute geriatric unit