BZRA deprescribing | BZRA cessation | |||
---|---|---|---|---|
OR [95CI] | p value | OR [95CI] | p value | |
Demographic data | ||||
Agea | 1 [0.9;1.0] | .218 | 1 [0.9;1.0] | .085 |
Comorbidities | ||||
CIRS-Ga | 1 [1;1.1] | .110 | 1 [1.0;1.1] | .489 |
Depression | 1.2 [0.8;1.9] | .365 | 0.9 [0.5;1.7] | .809 |
Delirium | 1.2 [0.8;1.8] | .457 | 1.2 [0.7;2.1] | .474 |
Cognitive decline | 1.5 [1;2.3] | .066 | 1 [0.6;1.8] | .971 |
Anxiety | 1.2 [0.7;2.1] | .437 | 1 [0.5;2] | .991 |
Sleep disorder | 1.1 [0.6;2.1] | .780 | 1.7 [0.7;3.7] | .191 |
Administrative data | ||||
Admission directly to AGU | 1 | 1 | ||
Admission through emergency room | 1.1 [0.7; 1.9] | .651 | 0.7 [0.3;1.3] | .256 |
Admission from another ward | 1.5 [0.8; 2.6] | .193 | 1 [0.4;2] | .931 |
Length of staya | 1 [1;1] | .215 | 1 [1;1] | .116 |
Living in a nursing home | 1.3 [0.7;2.3] | .592 | 1.4 [0.6;3.2] | .527 |
Discharge to home | 1 | 1 | ||
Discharge to a nursing home | 1.5 [0.8;2.7] | .172 | 1.4 [0.6;2.9] | .387 |
Discharge to another ward | 0.8 [0.4;1.4] | .404 | 0.5 [0.2;1.1] | .124 |
Medications at admission | ||||
BZRA dosagea | 1.2 [1.0;1.4] | .020 | 0.5 [0.4;0.6] | <.001 |
Antipsychotic user | 0.5 [0.3;0.8] | .008 | 0.7 [0.3;1.3] | .236 |
Antidepressant user | 1.6 [1.1;2.4] | .027 | 1.4 [0.8;2.5] | .243 |
Miscellaneous | ||||
Intervention of a clinical pharmacist | 1.5 [0.9;2.3] | .162 | 0.8 [0.4;1.5] | .421 |
Identification of a BZRA-related adverse event by the treating physician | 4.5 [2.6;8] | <.001 | 2.4 [1.2;4.5] | .012 |