Table 1 Triggerlist from the Dutch guideline “Polypharmacy in the older patient” [13]
Trigger (adverse clinical event) | Often involved medication |
|---|---|
Fracture / fall | Psychotropic medication (falls)/ corticosteroids / antihypertensive drugs |
Collapse / hypotension / dizziness | Cardiac medication (antihypertensive drugs and antiarrhythmics)/ psychotropic medication |
Bleeding (GI tract)/ supratherapeutic INR | Anticoagulants Antiplatelet drugs NSAID |
Electrolyte imbalance / dehydration | Diuretics, ACEi, AII-blocker, NSAID, antidepressants |
Renal insufficiency | ACEi, AII-blocker, NSAID |
Hypo- or hyperglycaemia | Insulin/oral antidiabetics, Corticosteroids |
Heart failure | NSAID |
Obstipation / ileus | Opioids / calcium blockers |
Vomiting / diarrhea | Antibiotics |
Delirium / confusion / drowsiness | Psychotropic medication / cardiac medication / medication for micturition complaints / benzodiazepines |