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Table 3 Regression estimates (odds ratio’s and 95% confidence intervals) of the associations between the dual fatigability and mobility trajectories* and demographic and clinical characteristics

From: Determinants of trajectories of fatigability and mobility among older medical patients during and after hospitalization; an explorative study

Characteristic Low fatigability high mobility Improving fatigability high mobility High fatigability low mobility
Univariable analysis    
Demographic characteristics    
Age, per year Ref. 0.94 (0.79; 1.13) 1.03 (0.86; 1.23)
Female sex Ref. 0.87 (0.12; 6.21) 0.00 (0.05; 3.12)
Male sex Ref. Ref. Ref.
<12 years of education Ref. 0.57 (0.05; 6.08) 0.12 (0.01; 1.43)
≥12 years of education Ref. Ref. Ref.
Living alone Ref. 0.42 (0.05; 3.22) 0.90 (0.12; 7.03)
Living together Ref. Ref. Ref.
Clinical characteristics    
Frailty, per 0.01 point Ref. 1.08 (0.96; 1.21) 1.26 (1.08; 1.46)
No baseline disabilities Ref. Ref. Ref.
≥1 baseline disabilities Ref. 5.78 (0.55; 60.60) 60.00 (3.04; 1185)
No depressive symptoms Ref. Ref. Ref.
Depressive symptoms Ref. 0.38 (0.03; 5.27) 1.82 (0.16; 20.71)
Comorbidity§, per point Ref. 0.74 (0.47; 1.19) 0.77 (0.48; 1.26)
Length of stay, per day Ref. 1.11 (0.78; 1.59) 1.25 (0.87; 1.79)
Multivariable analysis    
Frailty, per 0.01 point Ref. 1.09 (0.91; 1.30) 1.36 (1.07; 1.74)
No baseline disabilities Ref. Ref. Ref.
≥1 baseline disabilities Ref. 5.04 (0.23; 109.14) 9.89 (0.14; 686.83)
Comorbidity§, per point Ref. 0.56 (0.41; 1.12) 0.27 (0.10; 0.74)
  1. *Trajectory groups were estimated by jointly modeling fatigability and mobility over four waves from hospital admission up to six months after discharge. The low fatigability high mobility trajectory was used as the reference category (Ref.)
  2. †.Frailty was assessed using the Frailty Index
  3. ‡.Depressive symptoms were positive when the Geriatric Depression Score was ≥5
  4. §Comorbidity was assessed using the Charlson Comorbidity Index