Table 3 Participant baseline clinical characteristics

 median

0.028

0.083

0.139

0.167

0.056

 Upper: lower quartile

[0: 0.083]

[0.028: 0.139]

[0.083: 0.194]

[0.111: 0.250]

[0.028: 0.111]

 Fit

1,273,304 (90.1%)

272,694 (70.7%)

120,357 (46.5%)

37,243 (31.2%)

1,703,598 (78.2%)

 Mild

127,029 (9.0%)

94,558 (24.5%)

99,154 (38.3%)

49,192 (41.2%)

369,933 (17.0%)

 Moderate

12,055 (0.9%)

16,167 (4.2%)

32,732 (12.6%)

25,360 (21.2%)

86,214 (3.4%)

 Severe

1188 (0.1%)

2055 (0.5%)

6882 (2.7%)

7686 (6.4%)

17,811 (0.8%)

 Atrial fibrillation

11,359 (0.8%)

15,381 (4.0%)

23,978 (9.3%)

17,553 (14.7%)

68,271 (3.1%)

 Coronary Artery Disease

16,176 (1.1%)

16,017 (4.2%)

12,015 (4.6%)

2419 (2.0%)

46,627 (2.1%)

 Dementia

7705 (0.6%)

7812 (2.0%)

18,748 (7.2%)

19,328 (16.2%)

53,593 (2.5%)

 Depression

271,343 (19.2%)

55,438 (14.4%)

37,418 (14.4%)

18,220 (15.3%)

382,419 (17.6%)

 Haemorrhagic Stroke

3938 (0.3%)

1959 (0.5%)

1733 (0.7%)

867 (0.7%)

8497 (0.4%)

 Heart Failure

6219 (0.4%)

8736 (2.3%)

14,976 (5.8%)

12,583 (10.5%)

42,514 (2.0%)

 Hypertension

265,702 (18.8%)

161,622 (41.9%)

136,905 (52.8%)

60,133 (50.3%)

624,362 (28.7%)

 Ischaemic Stroke

9833 (0.7%)

11,097 (2.9%)

15,836 (6.1%)

10,617 (8.9%)

47,383 (2.2%)

 Malignancy

48,115 (3.4%)

32,230 (8.4%)

29,796 (11.5%)

14,646 (12.3%)

124,787 (5.7%)

 Peripheral Arterial Disease

8144 (0.6%)

9541 (2.5%)

11,073 (4.3%)

4992 (4.2%)

33,750 (1.6%)

 Rheumatoid Arthritis

11,149 (0.8%)

6244 (1.6%)

5236 (2.0%)

2169 (1.8%)

24,798 (1.1%)

 Transient Ischaemic Attack

8065 (0.6%)

10,774 (2.8%)

15,795 (6.1%)

10,916 (9.1%)

45,550 (2.1%)

 Diabetes

89,567 (6.3%)

49,954 (13.0%)

37,755 (14.6%)

13,514 (11.3%)

190,790 (8.8%)

 Chronic Obstructive Pulmonary Disease

28,352 (2.0%)

22,538 (5.9%)

20,399 (7.9%)

7395 (6.2%)

78,684 (3.6%)

 Chronic Kidney Disease

83,821 (5.9%)

42,059 (10.9%)

36,783 (14.2%)

19,404 (16.2%)

182,067 (8.4%)

 Asthma

95,438 (6.8%)

31,682 (8.2%)

20,747 (8.0%)

6365 (5.3%)

154,232 (7.1%)

 Osteoporosis

26,939 (1.9%)

21,884 (5.7%)

24,155 (9.3%)

14,096 (11.8%)

87,074 (4.0%)

 Morbid obesity risk group

46,465 (3.3%)

9516 (2.5%)

3799 (1.5%)

697 (0.6%)

60,477 (2.8%)

 Underweight

10,660 (1.2%)

4749 (1.6%)

6520 (3.5%)

5547 (8.8%)

27,476 (1.9%)

 Normal

270,394 (29.3%)

88,178 (29.9%)

70,979 (37.9%)

31,659 (50.4%)

461,210 (31.4%)

 Overweight

350,099 (38.0%)

119,969 (40.7%)

72,079 (38.4%)

18,858 (30.3%)

561,005 (38.2%)

 Obese

290,704 (31.5%)

82,017 (27.8%)

37,970 (20.3%)

6743 (10.7%)

417,434 (28.5%)

 Missing ^b

491,719 (34.8%)

90,561 (23.5%)

71,577 (27.6%)

56,674 (47.4%)

710,531 (32.6%)

 Flu vaccination

248,157 (17.6%)

269,364 (69.9%)

187,976 (72.5%)

71,906 (60.2%)

777,403 (35.7%)

 Pneumococcal vaccination

119,926 (8.5%)

231,908 (60.2%)

184,638 (71.3%)

77,218 (64.6%)

613,690 (28.2%)

 Non-smoker

539,051 (40.7%)

138,073 (37.9%)

94,660 (39.7%)

51,381 (52.4%)

823,165 (40.6%)

 Ex-smoker

437,970 (33.0%)

157,393 (43.2%)

109,868 (46.1%)

37,801 (38.5%)

743,032 (36.7%)

 Active smoker

348,396 (26.3%)

68,858 (18.9%)

33,807 (14.2%)

8904 (9.1%)

459,965 (22.7%)

 Missing ^b

88,159 (6.2%)

21,150 (5.5%)

20,790 (8.0%)

21,395 (17.9%)

151,494 (7.0%)

 median

4

18

32

39

8

 Upper: lower quartile

[0: 15]

[4: 42]

[12: 60]

[16: 71]

[1: 29]