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Fig. 1 | BMC Geriatrics

Fig. 1

From: Do skeletal muscle composition and gene expression as well as acute exercise-induced serum adaptations in older adults depend on fitness status?

Fig. 1

Schematic overview of the study design. After SITLESS, participants were asked to participate in this sub-study. A muscle biopsy was conducted at least one week before the CPX. Muscle samples were used for Myosin-Heavy chain (MyH) isoform composition and gene expression analysis. Blood was sampled before (pre) and directly after the CPX (post), and serum protein expression determined. Participants were classified according to the VO2peak measured during CPX by spiroergometry into HPF and LPF. (SITLESS: multinational 16-week long-intervention study to promote physical activity in the elderly population; CPX: cardiopulmonary exercise test; VO2peak: peak oxygen consumption; HPF: high physical fitness group; LPF: low physical fitness group)

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