Table 3 Univariate analysis of risk factors for anastomotic leakage in patients after resection with primary anastomosis for left-sided colorectal cancer

Gender; n (%)

Female

391 (93.8%)

26 (6.2%)

0.005

Male

427 (88.4%)

56 (11.6%)

CCI; n (%)

≤5

602 (92.6%)

48 (7.4%)

0.004

> 5

216 (86.4%)

34 (13.6%)

Ischemic heart disease; n (%)

Yes

39 (90.7%)

4 (9.3%)

0.999

No

779 (90.9%)

78 (9.1%)

Diabetes mellitus; n (%)

Yes

82 (86.3%)

13 (13.7%)

0.101

No

736 (91.4%)

69 (8.6%)

Cerebrovascular disease; n (%)

Yes

25 (92.6%)

2 (7.4%)

0.999

No

793 (90.8%)

80 (9.2%)

Chronic kidney failure; n (%)

Yes

12 (92.3%)

1 (7.7%)

0.999

No

806 (90.9%)

81 (9.1%)

Neoadjuvant treatment; n (%)

Yes

169 (88.0%)

23 (12.0%)

0.119

No

649 (91.7%)

59 (8.3%)

Tumor localization; n (%)

Rectum

458 (89.3%)

55 (10.7%)

0.132

Rectosigmoid

112 (91.8%)

10 (8.2%)

Sigmoid

248 (93.6%)

17 (6.4%)

T; n (%)

T0–2

284 (94.4%)

17 (5.6%)

0.010

T3–4

534 (89.1%)

65 (10.9%)

M; n (%)

M0

740 (91.4%)

70 (8.6%)

0.142

M1

78 (86.7%)

12 (13.3%)

Stage; n (%)

0

11 (91.7%)

1 (8.3%)

0.290

I

221 (93.4%)

15 (6.6%)

II

246 (91.4%)

23 (8.6%)

III

272 (90.1%)

30 (9.9%)

IV

78 (85.7%)

13 (14.3%)

Ligation of inferior mesenteric artery; n (%)

High

631 (90.5%)

66 (9.5%)

0.610

Low

167 (91.8%)

15 (8.2%)

Simultaneous operation; n (%)

Yes

73 (86.9%)

11 (13.1%)

0.183

No

745 (91.3%)

71 (8.7%)

Anastomosis level from anal verge; n (%)

≤5 cm

155 (89.1%)

19 (10.9%)

0.023

6–12 cm

255 (87.0%)

38 (13.0%)

> 12 cm

259 (93.8%)

17 (6.2%)

Approach of surgery; n (%)

Open

391 (88.5%)

51 (11.5%)

0.013

Minimally invasive

427 (93.2%)

31 (6.8%)

Age; n (%)

NE group (≤75 years)

675 (91.5%)

63 (8.5%)

0.201

E group (>75 years)

143 (88.3%)

19 (11.7%)