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Table 3 Independent predictors for MACE

From: Outcomes between prediabetes and type 2 diabetes mellitus in older adults with acute myocardial infarction in the era of newer-generation drug-eluting stents: a retrospective observational study

Variables

Unadjusted

 

Adjusted

 

HR (95% CI)

p value

HR (95% CI)

p value

Group A vs. Group B

1.319 (1.015–1.714)

0.039

1.363 (1.102–1.815)

0.016

Group A vs. Group C

1.620 (1.274–2.061)

< 0.001

1.455 (1.135–1.864)

0.003

Group B vs. Group C

1.231 (1.018–1.488)

0.032

1.099 (0.902–1.339)

0.349

Age

1.019 (1.005–1.033)

0.007

1.315 (1.109–1.666)

< 0.001

Male

1.175 (0.994–1.389)

0.058

1.198 (1.032–1.390)

0.017

LVEF < 40%

2.396 (1.994–2.880)

< 0.001

1.926 (1.592–2.330)

< 0.001

STEMI

1.182 (1.001–1.397)

0.049

1.289 (1.083–1.534)

0.004

Cardiogenic shock

1.853 (1.378–2.491)

< 0.001

1.626 (1.025–2.031)

0.005

CPR on admission

4.681 (3.726–5.881)

< 0.001

3.746 (2.948–4.760)

< 0.001

Killip class III/IV

2.840 (2.459–3.280)

< 0.001

1.550 (1.312–1.830)

< 0.001

Hypertension

1.097 (0.922–1.306)

0.295

1.002 (0.837–1.199)

0.984

NT-ProBNP

1.000 (0.999–1.001)

< 0.001

1.002 (1.000–1.003)

0.011

eGFR < 60 mL/min/1.73m2

1.783 (1.501–2.117)

< 0.001

1.415 (1.319–1.766)

< 0.001

Clopidogrel

1.037 (0.858–1.254)

0.705

1.195 (0.993–1.532)

0.159

Ticagrelor

1.366 (1.035–1.804)

0.028

1.562 (1.095–2.228)

0.014

Cilostazole

1.275 (1.016–1.600)

0.036

1.157 (0.919–1.457)

0.215

Beta-blocker

2.599 (2.189–3.087)

< 0.001

1.676 (1.379–2.037)

< 0.001

ACEI

2.154 (1.808–2.566)

< 0.001

1.853 (1.550–2.215)

< 0.001

ARB

1.020 (0.884–1.176)

0.788

1.195 (1.003–1.423)

0.046

Lipid lowering agent

2.588 (2.167–3.089)

< 0.001

1.851 (1.525–2.246)

< 0.001

Single-vessel disease

1.426 (1.196–1.699)

< 0.001

1.087 (0.881–1.343)

0.436

Multivessel disease

1.434 (1.202–1.710)

< 0.001

1.249 (1.032–1.510)

0.022

ACC/AHA type B2/C

1.274 (1.031–1.575)

0.025

1.363 (1.101–1.688)

0.005

Pre-PCI TIMI flow grade 2/3

1.023 (0.901–1.162)

0.725

1.071 (0.936–1.225)

0.319

Number of stent

1.155 (1.054–1.266)

0.002

1.089 (0.982–1.207)

0.105

  1. HR hazard ratio, CI confidence interval, Group A normoglycemia, Group B prediabetes, Group C T2DM, LVEF left ventricular ejection fraction, STEMI ST-segment elevation myocardial infarction, eGFR estimated glomerular filtration rate, CPR cardiopulmonary resuscitation, ACC/AHA American College of Cardiology/American Heart Association, IVUS intravascular ultrasound