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Table 2 Single Predictor Logistic Regressions of Patient Characteristics to Predict Hospital Mortality (N = 4783)(Expired versus Discharged Alive)

From: Geriatrics-focused indicators predict mortality more than age in older adults hospitalized with COVID-19

Patient Characteristics

Expired

M (SD) or n (%)

Discharged Alive

M (SD) or n (%)

OR (95% CI)

P-value

Age

79.20 (8.48)

76.31 (8.20)

1.04 (1.03, 1.05)a

< 0.001*

Sex

 Male

1045 (39.09%)

1628 (60.91%)

1.31 (1.17, 1.48)

< 0.001*

 Female

693 (32.84%)

1417 (67.16%)

1 (ref)

 

Race

 Black

304 (31.31%)

667 (68.69%)

0.73 (0.63, 0.86)

< 0.001*

 Asian

164 (42.27%)

224 (57.73%)

1.18 (0.95, 1.47)

0.142

 White

869 (38.33%)

1398 (61.67%)

1 (ref)

–

 Other

336 (34.60%)

635 (65.40%)

0.85 (0.73, 0.99)

0.04*

 Not available

65 (34.95%)

121 (65.05%)

0.86 (0.63, 1.18)

0.361

Ethnicity

 Hispanic or Latino

242 (33.80%)

474 (66.20%)

0.87 (0.74, 1.03)

0.12

 Not Hispanic or Latino

1403 (36.87%)

2402 (63.13%)

1 (ref)

 

Insurance

 Medicaid or Uninsured

108 (35.06%)

200 (64.94%)

0.94 (0.74, 1.20)

0.63

 Medicare or Private

1630 (36.35%)

2854 (63.65%)

1 (ref)

 

Comorbidities

 Diabetes Mellitus

  Yes

662 (37.85%)

1087 (62.15%)

1.11 (0.98, 1.25)

0.10

  No

1076 (35.46%)

1958 (64.54%)

1 (ref)

 

 Hypertension

  Yes

1008 (58.00%)

730 (42.00%)

0.814 (0.72, 0.92)

< 0.001*

  No

1916 (62.92%)

1129 (37.08%)

1 (ref)

 

 Chronic Obstructive Pulmonary Disease

  Yes

179 (43.13%)

236 (56.87%)

1.37 (1.12, 1.68)

0.003*

  No

1559 (35.69%)

2809 (64.31%)

1 (ref)

 

 Intertitial Lung Disease

  Yes

216 (67.29%)

105 (32.71%)

3.97 (3.12, 5.06)

< 0.001*

  No

1522 (34.11%)

2940 (65.89%)

1 (ref)

 

 Asthma

  Yes

81 (33.89%)

158 (66.11%)

0.89 (0.68, 1.18)

0.420

  No

1657 (36.47%)

2887 (63.53%)

1 (ref)

 

 Cancer

  Yes

176 (41.31%)

250 (58.69%)

1.26 (1.03, 1.54)

.03*

  No

1562 (35.85%)

2795 (64.15%)

1 (ref)

 

 Coronary Artery Disease

  Yes

124 (47.51%)

137 (52.49%)

1.63 (1.27, 2.10)

< 0.001*

  No

1614 (35.69%)

2908 (64.31%)

1 (ref)

 

 Atrial Fibrillation

  Yes

321 (45.02%)

392 (54.98%)

1.53 (1.31, 1.80)

< 0.001*

  No

1417 (34.82%)

2653 (65.18%)

1 (ref)

 

 Chronic Kidney Disease

  Yes

356 (45.24%)

431 (54.76%)

1.56 (1.34, 1.82)

< 0.001*

  No

1382 (34.58%)

2614 (65.42%)

1 (ref)

 

 Dementia

  Yes

290 (46.10%)

339 (53.90%)

1.60 (1.35, 1.89)

< 0.001*

   No

1448 (34.86%)

2706 (65.14%)

1 (ref)

 

BMI

 Underweight BMI below 18.5

46 (44.23%)

58 (55.77%)

1.44 (0.96, 2.16)

0.080

 Normal 18.5 to 24.9

361 (35.53%)

655 (64.47%)

1 (ref)

 

 Overweight, 25 to 29.9

421 (33.90%)

821 (66.10%)

0.93 (0.78, 1.11)

0.417

 Obese, 30 or above

323 (32.86%)

660 (67.14%)

0.89 (0.74, 1.07)

0.208

Comorbidity Index (CCI-age, continuous)b

3.85 (2.97)

3.18 (2.76)

1.08 (1.06, 1.11)

< 0.001*

Residence Prior to Admission

 Facility

495 (48.82%)

519 (51.18%)

1.94 (1.68, 2.23)

< 0.001*

 Home

1243 (32.98%)

2526 (67.02%)

1 (ref)

 

Advanced Directives

 Early DNRc

  Yes

181 (64.87%)

98 (35.13%)

3.50 (2.71, 4.50)

< 0.001*

  No

1557 (34.57%)

2947 (65.43%)

1 (ref)

 

Severity of Illness on Presentation

 MEWS d

  Severely-ill

993 (68.15%)

464 (31.85%)

6.79 (5.90, 7.80)

< 0.001*

  Not severely-ill

684 (23.97%)

2169 (76.03%)

1 (ref)

 

First documented oxygen

 Nasal cannulae

1140 (36.39%)

1993 (63.61%)

2.58 (2.16, 3.08)

< 0.001*

 Nonrebreatherf

254 (56.07%)

199 (43.93%)

5.75 (4.49, 7.36)

< 0.001*

 Mechanical ventilation

166 (76.50%)

51 (23.50%)

14.67 (10.30, 20.88)

< 0.001*

 Room air

178 (18.16%)

802 (81.84%)

1 (ref)

–

  1. a Odds of death expected to increase 4% with one- year increase in age
  2. b CCI Charlson Comorbidity Index
  3. c DNR Do Not Resuscitate
  4. d MEWS Modified Early Warning Score
  5. e Nasal cannula includes ventimask
  6. f Nonrebreather includes high flow and non-invasive ventilation
  7. * p ≤ 0.05