Parameters | Fall at five years (N = 400) | Fall-related Injuries at five years (N = 400) | Disability at five years (N = 400) | ||||||
---|---|---|---|---|---|---|---|---|---|
Faller (n = 136) | Non-faller (n = 264) | p Value | Injured (n = 97) | Non-injured (n = 303) | p Value | Disabled (n = 61) | Non-disabled (n = 339) | p Value | |
Age | 68.98 ± 6.17 | 67.63 ± 5.33 | <.001* | 69.37 ± 6.55 | 67.55 ± 5.25 | .004* | 70.66 ± 6.21 | 67.10 ± 4.90 | <.001* |
Sex: | |||||||||
 Men | 45 (33.1) | 134 (51.3) | <.001* | 36 (37.1) | 143 (47.2) | .085 | 23 (37.7%) | 159 (46.6%) | .211 |
 Women | 91 (66.9) | 130 (48.7) |  | 61 (62.9) | 160 (52.8) |  | 38 (62.3%) | 180 (53.4%) |  |
Ethnic: | |||||||||
 Malay | 49 (36.0) | 113 (42.9) | .197 | 35 (36.1) | 118 (41.8) | .351 | 26 (42.6%) | 136 (39.9%) | .777 |
 Non-Malay | 87 (64.0) | 151 (57.1) |  | 62 (23.1) | 185 (58.2) |  | 35 (57.4%) | 203 (60.1%) |  |
Education (years) | 5.20 ± 3.98 | 5.72 ± 4.08 | .048* | 5.60 ± 4.57 | 6.42 ± 4.52 | .113 | 4.02 ± 3.47 | 6.77 ± 4.62 | <.001* |
Living alone | 13 (9.6) | 17 (6.5) | .318 | 15 (15.5) | 25 (7.1) | .015* | 8 (13.1%) | 21 (6.2%) | .062 |
Smoker | 29 (21.3) | 60 (23.0) | .800 | 24 (24.7) | 80 (22.6) | .684 | 17 (27.9%) | 71 (20.8%) | .240 |
Household income | 1285.83 ± 1856.91 | 1442.01 ± 2797.75 | .296 | 1249.90 ± 1821.05 | 1782.34 ± 2536.02 | .055 | 878.57 ± 1119.84 | 1852.85 ± 2576.85 | <.001* |
Health Conditions: | |||||||||
 Diabetes | 38 (27.9) | 60 (23.0) | .327 | 27 (27.8) | 86 (24.3) | .509 | 20 (32.8) | 80 (23.7) | .149 |
 Hypertension | 68 (50.0) | 123 (47.1) | .598 | 46 (47.4) | 172 (48.6) | .909 | 34 (55.7) | 157 (46.4) | .211 |
 Hypercholesterolemia | 48 (35.3) | 73 (28.0) | .137 | 34 (35.1) | 106 (29.9) | .386 | 19 (31.1) | 102 (30.2) | .881 |
 Heart Disease | 15 (11.0) | 16 (6.1) | .113 | 11 (11.3) | 26 (7.3) | .212 | 9 (14.8) | 23 (6.8) | .068 |
Nutritional assessments | |||||||||
 BMI (kg/m2) | 25.76 ± 4.18 | 25.44 ± 4.22 | .386 | 24.21 ± 3.84 | 25.67 ± 4.11 | .002* | 26.60 ± 4.13 | 25.31 ± 4.02 | .023* |
 CC (cm) | 33.48 ± 3.64 | 33.67 ± 3.52 | .418 | 33.29 ± 3.33 | 34.55 ± 3.54 | .002* | 34.13 ± 3.18 | 34.48 ± 3.52 | .469 |
 WC (cm) | 88.03 ± 10.68 | 88.14 ± 10.51 | .868 | 86.85 ± 11.09 | 89.60 ± 10.41 | .024* | 92.94 ± 9.36 | 88.73 ± 10.52 | .004* |
 MUAC (cm) | 28.59 ± 3.25 | 28.58 ± 3.18 | .949 | 27.63 ± 3.10 | 29.19 ± 3.27 | <.001* | 29.38 ± 3.22 | 29.01 ± 3.12 | .396 |
Body composition | |||||||||
 % Body Fat | 40.32 ± 10.13 | 38.93 ± 10.49 | .039* | 38.28 ± 9.99 | 38.52 ± 10.13 | .838 | 43.19 ± 10.28 | 37.91 ± 9.89 | <.001* |
 Fat mass (kg) | 25.00 ± 9.28 | 24.46 ± 8.81 | .359 | 22.97 ± 9.15 | 24.90 ± 8.76 | .057 | 27.91 ± 8.69 | 24.25 ± 8.72 | .003* |
 Fat free mass (kg) | 35.76 ± 7.01 | 37.42 ± 8.13 | .001* | 35.74 ± 7.47 | 38.87 ± 8.12 | .001* | 36.03 ± 7.20 | 38.80 ± 8.23 | .014* |
 Skeletal muscle mass (kg) | 18.93 ± 4.17 | 19.94 ± 4.86 | .001* | 18.92 ± 4.47 | 20.81 ± 4.86 | .001* | 19.10 ± 4.30 | 20.77 ± 4.93 | .013* |
Laboratory analysis | |||||||||
 FBS (mmol/l) | 5.79 ± 1.55 | 6.05 ± 1.96 | .038* | 5.69 ± 1.45 | 6.03 ± 2.23 | .222 | 43.19 ± 10.28 | 37.91 ± 9.89 | .866 |
 HbA1c (%) | 13.71 ± 1.93 | 14.24 ± 2.19 | .001* | 14.18 ± 2.81 | 14.57 ± 2.67 | .271 | 14.20 ± 2.24 | 14.54 ± 2.67 | .406 |
 Total cholesterol (mmol/l) | 5.37 ± 1.14 | 5.39 ± 1.07 | .780 | 5.21 ± 1.01 | 5.19 ± 1.00 | .899 | 5.00 ± 1.02 | 5.22 ± 1.01 | .159 |
 HDL (mmol/l) | 1.42 ± 0.36 | 1.40 ± 0.34 | .327 | 1.52 ± 0.38 | 1.44 ± 0.37 | .109 | 1.46 ± 0.37 | 1.46 ± 0.38 | .978 |
 LDL (mmol/l) | 3.29 ± 1.05 | 3.33 ± 0.98 | .620 | 3.04 ± 0.93 | 3.10 ± 0.91 | .610 | 5.00 ± 1.02 | 5.22 ± 1.01 | .192 |
 Albumin (g/l) | 42.76 ± 2.41 | 42.94 ± 2.53 | .313 | 42.68 ± 2.65 | 43.05 ± 2.75 | .303 | 42.38 ± 2.40 | 43.07 ± 2.73 | .093 |
Psychosocial and functional status: | |||||||||
 GDS | 2.69 ± 2.31 | 2.43 ± 2.14 | .084 | 2.73 ± 2.43 | 2.58 ± 2.29 | .579 | 4.43 ± 3.48 | 2.52 ± 2.67 | <.001* |
 MOSS | 37.89 ± 14.95 | 40.24 ± 14.84 | .017* | 36.57 ± 16.13 | 37.50 ± 15.19 | .603 | 30.39 ± 16.89 | 38.18 ± 14.53 | <.001* |
 Loneliness | 3.34 ± 1.06 | 3.17 ± 0.74 | .003* | 3.29 ± 0.91 | 3.21 ± 0.84 | .421 | 3.34 ± 1.05 | 3.20 ± 0.79 | .022* |
 IADL | 12.76 ± 2.00 | 12.75 ± 1.84 | .904 | 13.13 ± 1.52 | 13.13 ± 1.59 | .977 | 12.77 ± 1.76 | 13.21 ± 1.53 | .046* |
 WHODAS | 6.28 ± 8.69 | 4.54 ± 6.55 | .010* | 7.03 ± 9.17 | 5.37 ± 7.52 | .001 | 8.66 ± 8.16 | 4.50 ± 7.03 | <.001* |
 ALQ | 39.25 ± 10.35 | 39.82 ± 10.28 | .404 | 39.91 ± 10.52 | 41.99 ± 9.89 | .124 | 37.08 ± 9.82 | 42.71 ± 9.91 | <.001* |
Cognitive assessment | |||||||||
 MMSE | 23.45 ± 4.64 | 23.86 ± 4.19 | .153 | 23.29 ± 5.56 | 24.66 ± 4.08 | .008* | 22.36 ± 5.41 | 24.85 ± 3.97 | <.001* |
 MoCA | 19.31 ± 5.56 | 19.82 ± 5.37 | .156 | 20.67 ± 5.32 | 23.29 ± 5.56 | .130 | 18.05 ± 5.57 | 21.08 ± 5.15 | <.001* |
 Span Digit | 7.57 ± 2.48 | 7.73 ± 2.32 | .321 | 7.60 ± 2.53 | 8.16 ± 2.47 | .052 | 7.67 ± 2.32 | 8.14 ± 2.52 | .154 |
 RAVLT | 40.12 ± 9.69 | 40.42 ± 9.54 | .640 | 39.84 ± 9.49 | 40.64 ± 10.36 | .499 | 37.17 ± 9.31 | 41.01 ± 10.42 | .008* |
 Digit symbol | 5.12 ± 2.58 | 5.39 ± 2.73 | .122 | 5.72 ± 3.01 | 6.21 ± 3.21 | .193 | 4.68 ± 2.00 | 6.43 ± 3.27 | <.001* |
Fitness test: | |||||||||
 2-min step test | 63.83 ± 26.57 | 66.13 ± 22.89 | .156 | 67.71 ± 28.14 | 69.20 ± 24.11 | .606 | 55.43 ± 28.69 | 70.83 ± 23.65 | <.001* |
 Chair stand test | 10.35 ± 3.00 | 10.49 ± 2.97 | .461 | 10.48 ± 3.40 | 10.89 ± 3.09 | .257 | 9.20 ± 2.67 | 11.18 ± 3.08 | <.001* |
 Chair sit and reach test | 0.21 ± 11.73 | − 0.44 ± 10.75 | .378 | 1.29 ± 9.79 | 1.94 ± 9.85 | .570 | 4.48 ± 10.22 | 1.55 ± 9.76 | .034* |
 TUG test | 10.43 ± 2.75 | 10.18 ± 2.61 | .156 | 9.60 ± 2.78 | 9.46 ± 2.48 | .633 | 10.76 ± 2.61 | 9.20 ± 2.41 | <.001* |
 Back scratch test | 14.09 ± 12.53 | 13.66 ± 11.95 | .599 | 13.80 ± 11.15 | 13.70 ± 12.55 | .946 | 18.67 ± 13.12 | 12.65 ± 11.97 | <.001* |
MCI | 15 (11.1%) | 38 (14.4%) | .355 | 11 (10.1) | 49 (14.4) | .161 | 35 (57.4%) | 124 (36.5%) | .039* |
Physical frailty | 67 (49.6%) | 100 (38.0%) | .032* | 13 (11.9) | 19 (5.6) | .025* | 3 (4.9%) | 50 (14.7%) | .003* |
Cognitive frailty | 82 (60.3%) | 95 (36.4%) | <.001* | 52 (47.7) | 125 (36.8) | .028* | 36 (59.0%) | 124 (36.5%) | .002* |
Nutrient intake | |||||||||
 Energy (kcal) | 1633 ± 4.71 | 1698 ± 490 | .047* | 1608 ± 436 | 1656 ± 432 | .345 | 1549 ± 438 | 1658 ± 427 | .076 |
 Protein (g) | 70.30 ± 22.86 | 71.91 ± 21.72 | .283 | 69.16 ± 22.78 | 69.70 ± 20.09 | .828 | 68.25 ± 19.78 | 69.92 ± 21.10 | .576 |
 Carbohydrate (g) | 217.67 ± 74.41 | 232.94 ± 80.85 | .004* | 205.08 ± 69.70 | 223.10 ± 70.92 | .032* | 202.29 ± 68.81 | 221.53 ± 69.56 | .053 |
 Fat (g) | 53.27 ± 20.84 | 52.82 ± 18.86 | .730 | 56.69 ± 19.71 | 53.36 ± 17.86 | .125 | 51.79 ± 18.64 | 54.13 ± 18.06 | .368 |
 Fibre (g) | 4.26 ± 2.83 | 4.02 ± 2.42 | .155 | 4.66 ± 2.88 | 4.65 ± 2.57 | .976 | 4.06 ± 2.13 | 4.81 ± 2.81 | .022* |
 Vitamin C (mg) | 116.08 ± 82.15 | 124.47 ± 88.82 | .144 | 134.07 ± 77.29 | 134.40 ± 86.99 | .973 | 125.42 ± 88.04 | 136.29 ± 86.91 | .383 |
 Vitamin D (μg) | 0.30 ± 0.99 | 0.27 ± 0.81 | .696 | 0.38 ± 0.84 | 0.34 ± 0.99 | .742 | 0.24 ± 0.87 | 0.36 ± 0.99 | .360 |
 Vitamin E (mg) | 14.45 ± 68.58 | 8.58 ± 41.43 | .105 | 7.51 ± 19.83 | 5.96 ± 14.02 | .399 | 8.04 ± 24.58 | 6.15 ± 14.37 | .419 |
 Thiamin (mg) | 1.26 ± 2.48 | 1.56 ± 3.81 | .148 | 1.10 ± 2.06 | 1.51 ± 3.11 | .235 | 1.64 ± 3.33 | 1.54 ± 3.31 | .836 |
 Riboflavin (mg) | 1.23 ± 0.50 | 1.24 ± 0.47 | .732 | 1.25 ± 0.47 | 1.25 ± 0.45 | .987 | 1.11 ± 0.43 | 1.29 ± 0.46 | .006* |
 Niacin (mg) | 10.51 ± 4.59 | 10.47 ± 3.76 | .879 | 10.63 ± 4.82 | 10.04 ± 3.47 | .198 | 9.26 ± 2.82 | 10.39 ± 4.00 | .040* |
 Sodium (mg) | 1447.62 ± 564.41 | 1517.57 ± 1080.13 | .291 | 1421.61 ± 785.88 | 1443.61 ± 902.77 | .830 | 1739.82 ± 1310.0 | 1422.52 ± 798.02 | .079 |
 Calcium (mg) | 512.31 ± 424.24 | 529.64 ± 234.93 | .281 | 517.19 ± 224.21 | 509.32 ± 220.00 | .764 | 480.69 ± 215.99 | 515.61 ± 223.39 | .272 |
 Iron (mg) | 13.53 ± 5.42 | 13.81 ± 5.19 | .436 | 13.47 ± 5.18 | 13.65 ± 4.77 | .749 | 13.24 ± 4.73 | 13.76 ± 4.85 | .451 |
 Zinc (mg) | 3.63 ± 1.81 | 3.75 ± 2.00 | .334 | 3.59 ± 1.58 | 3.77 ± 1.88 | .527 | 3.50 ± 1.88 | 3.75 ± 1.87 | .359 |