BMC Geriatrics

Table 2 Multivariable linear regression evaluating biomarkers linking to muscle strength, muscle mass, fat mass and bone mass adjusted for age

From: Serum concentrations of oxytocin, DHEA and follistatin are associated with osteoporosis or sarcopenia in community-dwelling postmenopausal women

Handgrip (right)	R2	beta	95%CI	P value
DHEA	0.611	0.403	0.352 ~ 0.454	0.041
T2	0.005	−1.224	−4.6854-2.236	0.484
E2	0.002	−0.013	− 0.078-0.051	0.682
Gait speed		beta	95%CI	P value
DHEA	0.234	0.58	0.576 ~ 0.587	0.004
T2	0.006	−1.198	−4.389-1.993	0.458
E2	0.002	0.013	−0.046-0.073	0.657
Lean mass		beta	95%CI	P value
Follistatin	0.365	−0.28	−0.309 ~ − 0.243	0.010
Oxytocin	0.272	0.35	0.306 ~ 0.398	0.036
Fat mass		beta	95%CI	P value
Myostatin	0.362	0.92	0.881 ~ 0.960	0.021
ASMI		beta	95%CI	P value
Myostatin	0.356	−0.31	−0.352 ~ −0.251	0.032
Follistatin	0.227	−0.48	−0.529 ~ − 0.430	0.042
BMD (lumbar spine)		beta	95%CI	P value
CTX	0.572	−0.42	−0.420 ~ − 0.412	< 0.001
DHEA	0.415	0.38	0.338 ~ 0.414	0.022
T2	0.003	0.025	−0.065-0.114	0.586
E2	0.027	0.001	0.000–0.003	0.123
BMD (femur neck)		beta	95%CI	P value
Oxytocin	0.347	0.61	0.576 ~ 0.642	0.014
BMD (total hip)		beta	95%CI	P value
DHEA	0.285	0.52	0.480 ~ 0.551	0.017
T2	0.005	0.031	−0.065-0.127	0.521
E2	0.002	0.001	−0.002-0.001	0.665
Oxytocin	0.366	0.59	0.535–0.651	0.044

R2 coefficient of determination, Beta standardized regression coefficients, P-value significant level at p < 0.05. DHEA Dehydroepiandrosterone, E2 Estradiol, T2 Testosterone, ASMI Appendicular skeletal mass index, BMD Bone mineral density, CTX C-telopeptide collagen crosslinks

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