Skip to main content

Table 1 Descriptive characteristics of the studied population

From: Serum concentrations of oxytocin, DHEA and follistatin are associated with osteoporosis or sarcopenia in community-dwelling postmenopausal women

Variable Age<65
(n = 171)
65 ≤ Age<75
(n = 185)
75 ≤ Age
(n = 122)
P value
Age (years) 58.0 ± 4.0 69.21 ± 2.9 79.8 ± 3.6 < 0.001
Age of menopause (years) 50.66 ± 4.2 49.89 ± 3.0 50.1 ± 2.9 0.48
BMI (kg/m2) 23.94 ± 3.3 23.99 ± 2.9 23.75 ± 4.1 0.95
Grip strength (kg)
 Left 20.18 ± 3.7 18.74 ± 4.1 15.96 ± 4.2 < 0.001
 Right 22.88 ± 4.4 21.15 ± 4.0 18.12 ± 4.8 < 0.001
 Gait speed (m/s) 1.15 ± 0.19 1.08 ± 0.20 0.87 ± 0.25 < 0.001
Physical exercise (%)
 No 11.8 22.7 48.1 0.008
 Low 39.3 38.8 36.1 0.65
 High 48.9 38.5 15.8 < 0.001
Milk consumption (%)
 No 33.6 38.3 45.7 0.08
 Low 34.3 36.4 38.1 0. 17
 High 32.1 25.3 16.2 0.03
History of fragility facture (%) 11.5 20.3 26.6 0.002
LH (lU/l) 20.43 (15.49–24.16) 17.45 (13.10–26.10) 20.67 (16.15–25.25) 0.453
FSH (lU/l) 53.03 (45.73–64.53) 49.16 (41.51–71.78) 56.59 (50.98–80.66) 0.174
E2 (pmol/l) 40.00 (37.00–45.75) 37.00 (37.00–46.00) 39.00 (37.00–62.75) 0.445
T2 (pg/ml) 0.73 (0.59–0.85) 0.67 (0.56–0.88) 0.99 (0.66–1.20) 0.048
DHEA (ng/ml) 47.08 ± 12.3 40.75 ± 11.5 37.0 ± 11.3 0.009
PTH (pg/ml) 38.6 (32.3–47.4) 40.80 (34.38–47.60) 39.9 (27.75–57.70) 0.637
25OHD (ng/ml) 19.75 (14.9–25.85) 21.05 (15.65–27.65) 23.90 (17.80–27.90) 0.562
CTX (pg/ml) 441.65 ± 198.1 365.75 ± 177.6 369.4 ± 187.4 0.07
PINP (ng/ml) 48.18 ± 17.4 43.97 ± 16.4 40.1 ± 14.5 0.12
Follistatin (ng/ml) 14.45 ± 4.9 15.61 ± 4.5 16.9 ± 4.4 0.19
Myostatin (ng/ml) 4.08 ± 1.6 3.61 ± 1.1 3.4 ± 1.5 0.18
Oxytocin (pg/ml) 508.10 (338.33–1245.42) 380.92 (183.96–722.48) 243.53 (191.99–351.53) 0.008
BDNF (ng/ml) 32.06 ± 11.2 29.51 ± 10.4 27.5 ± 11.1 0.33
BMD (g/cm2)
 total femur 0.822 ± 0.11 0.765 ± 0.11 0.692 ± 0.14 < 0.001
 femoral neck 0.646 ± 0.08 0.612 ± 0.09 0.572 ± 0.12 < 0.001
 lumbar spine 0.802 ± 0.12 0.780 ± 0.12 0.751 ± 0.14 0.24
 WHR (waist/hip) 1.09 ± 0.16 1.11 ± 0.14 1.09 ± 0.13 0.76
 Fat mass (kg) 20.91 ± 4.5 20.73 ± 4.4 19.63 ± 5.2 0.50
 Lean mass (kg) 38.06 ± 4.5 36.82 ± 3.6 34.24v4.4 0.001
 ASMI (kg/m2) 6.25 ± 0.71 6.18 ± 0.56 5.92 ± 0.87 0.13
  1. LH Luteinizing hormone, FSH Follicle stimulating hormone, DHEA Dehydroepiandrosterone, E2 Estradiol, T2 Testosterone, P1NP N-terminal propeptide of type I collagen, CTX Cross-linked C-telopeptide of type I collagen, PTH Parathyroid hormone, 25OHD Serum 25(OH)D, BDNF Brain-derived neurotrophic factor, BMI Body mass index, BMD Bone mineral density, WHR Waist/hip ratio, ASMI Appendicular skeletal mass index