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Table 2 Associations of primary exposure (being nonagenarian) with mortality and management strategies in a multilevel logistic regression model

From: Management and outcomes in critically ill nonagenarian versus octogenarian patients

  octogenarians nonagenarians p-value model-1 model-2
Treatment withheld 27% (1945) 35% (279) < 0.001 aOR 1.54
(95% CI 1.22–1.94; p = < 0.001)
aOR 0.95
(95% CI 0.67–1.36; p = 0.79)
Treatment withdrawn 14% (1026) 13% (102) 0.24 aOR 1.03
(95% CI 0.77–1.39; p = 0.82)
aOR 0.73
(95% CI 0.48–1.10; p = 0.13)
NIV 25% (1794) 21% (168) 0.014 aOR 0.79
(95% CI 0.61–1.03; p = 0.08)
aOR 0.85
(95% CI 0.59–1.22; p = 0.36)
Mechanical Ventilation 52% (3685) 41% (324) < 0.001 aOR 0.72
(95% CI 0.56–0.93; p = 0.01)
aOR 1.26
(95% CI 0.85–1.87; p = 0.26)
RRT 11% (816) 4% (33) < 0.001 aOR 0.32
(95% CI 0.19–0.53; p = < 0.001)
aOR 0.55
(95% CI 0.28–1.08; p = 0.08)
Vasoactive drugs 59% (4179) 52% (414) < 0.001 aOR 0.74
(95% CI 0.58–0.95; p = 0.017)
aOR 0.90
(95% CI 0.60–1.35; p = 0.62)
30d Mortality 40% (2743) 44% (337) 0.029 aOR 1.39
(95% CI 1.13–1.72); p = 0.002)
aOR 1.25
(95% CI 0.90–1.74; p = 0.19)
ICU-Mortality 27% (1921) 27% (213) 0.97 aOR 1.10
(95% CI 0.87–1.40); p = 0.43)
aOR 0.91
(95% CI 0.63–1.32; p = 0.63)
  1. NIV Non-Invasive Ventilation, RRT renal replacement therapy, ICU Intensive Care Unit, aOR Adjusted Odds Ratio, 95% CI 95% Confidence Interval
  2. Model 1 - ICU cluster (the patient’s individual ICU) as random effect
  3. Model 2 - Model 1 plus patient level (SOFA, CFS, age, sex)