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Table 3 Cox regression analyses for the association between all-cause mortality and MMSE domains

From: Cognitive function assessed by Mini-mental state examination and risk of all-cause mortality: a community-based prospective cohort study

MMSE domains

HR (95% CI)

Model 1a

Model2b

Model 3c

orientation to time

2.00 (1.29, 3.11) **

1.40 (0.90, 2.18)

1.44 (0.88, 2.35)

orientation to place

1.30 (0.58, 2.93)

0.94 (0.39, 2.29)

1.01 (0.39, 2.62)

registration

1.07 (0.86, 1.33)

0.99 (0.80, 1.23)

0.95 (0.75, 1.20)

attention and calculation

1.49 (1.16, 1.92) **

1.22 (0.95, 1.56)

1.15 (0.87, 1.51)

recall

2.59 (1.22, 5.47) *

2.00 (0.85, 4.69)

1.16 (0.43, 3.18)

language

1.68 (1.25, 2.26) ***

1.47 (1.09, 1.96) *

1.31 (0.92, 1.87)

Number of impaired MMSE domains

 Continuous variable

1.51 (1.38, 1.65) ***

1.25 (1.13, 1.38) ***

1.12 (1.01, 1.25) *

Categorical variable

 0–1

1(Reference)

1(Reference)

1(Reference)

 2

1.86 (1.43, 2.41) ***

1.26 (0.97, 1.65)

1.14 (0.84, 1.54)

 3

2.49 (1.75, 3.53) ***

1.71 (1.19, 2.45) **

1.50 (0.98, 2.28)

 4

4.36 (2.44, 7.82) ***

2.97 (1.64, 5.38) **

2.14 (1.12, 4.09) *

  ≥ 5

11.56 (5.91, 22.61) ***

3.83 (1.91, 7.66) ***

2.29 (1.24, 5.04) *

P for trend

p < 0.001

p < 0.001

0.003

  1. Abbreviation: HR hazard ratio; CI confidence interval
  2. a adjusted for none
  3. b adjusted for age and sex
  4. c adjusted for age, sex, BMI, waistline, SBP, DBP, FPG, TC, HDL, LDL, TG, eGFR, education level, marital status, smoking status, drinking status, CHD, hypertension, diabetes mellitus, stroke, family history of dementia, dyslipidemia, antiplatelet agents, antihypertensive agents, hypoglycemic therapy, lipid-lowering therapy, and ADL impairment
  5. *P < 0.05
  6. **P < 0.01
  7. ***P < 0.001
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BMC Geriatrics

ISSN: 1471-2318

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