Table 1 Baseline characteristics of the included participants
Parameters | Young (n = 52) | Middle (n = 61) | Old (n = 42) | p-value |
|---|---|---|---|---|
Age (years) | 25.4 ± 0.4a,b | 50.1 ± 0.4b | 74.9 ± 0.5 | < 0.001 |
Female (%) | 28 (53.85) | 36 (59.01) | 16 (38.1) | 0.128c |
Weight (kg) | 61.5 ± 8.8 | 66.1 ± 12.1 | 64.7 ± 10.2 | 0.342d |
BMI (kg/m2) | 22.7 ± 3.2 | 23.3 ± 3.0 | 22.4 ± 2.5 | 0.441d |
Smoking (%) | 8 (15.38) | 18 (29.51) | 10 (23.81) | 0.369c |
Drinking (%) | 12 (23.08) | 12 (19.67) | 12 (19.05) | 0.157c |
SBP (mm Hg) | 116.25 ± 4.39 | 125.36 ± 5.26 | 128.46 ± 5.38 | 0.171d |
DBP (mm Hg) | 76.47 ± 1.42 | 78.25 ± 2.24 | 79.26 ± 3.14 | 0.203d |
LDL-C (mmol/L) | 2.0 ± 0.6 | 2.5 ± 0.6 | 2.8 ± 0.9 | 0.561d |
HDL-C (mmol/L) | 1.3 ± 0.2 | 1.2 ± 0.2 | 1.3 ± 0.3 | 0.457d |
TG (mmol/L) | 0.9 ± 0.2 | 1.0 ± 0.3 | 1.5 ± 0.9 | 0.614d |
TC (mmol/L) | 3.8 ± 0.8 | 4.3 ± 0.5 | 4.9 ± 1.2 | 0.648d |
GFR (ml/min) | 114.2 ± 13.5 | 109.7 ± 16.9 | 121.3 ± 25.9 | 0.798d |
Cr (μmol/L) | 73.9 ± 15.6 | 71.2 ± 12.3 | 81.7 ± 24.9 | 0.389d |
AST (U/L) | 18.6 ± 3.9 | 21.6 ± 6.2 | 25.4 ± 12.6 | 0.505d |
ALT (U/L) | 15.3 ± 7.2 | 24.1 ± 13.9 | 21.9 ± 16.7 | 0.661d |
UA (μmol/L) | 334.7 ± 58.2 | 310.1 ± 57.4 | 316.2 ± 61.3 | 0.298d |
Glucose (mmol/L) | 5.4 ± 0.2 | 5.3 ± 0.3 | 5.6 ± 0.7 | 0.412d |
HbA1c (%) | 4.6 ± 0.8 | 5.1 ± 0.7 | 4.8 ± 1.0 | 0.257d |