Table 1 Study Measures and Testing Occasions
Domain (purpose) | Measure | Description | Respondent | Testing Occasion |
|---|---|---|---|---|
PLWD cognitive status (descriptive, possible covariate) | Clinical Dementia Rating (CDR) [27] | Cognitive status | PLWD | Nurse visit |
PLWD physical function (descriptive, possible covariate) | Barthel Index [31] | CG proxy report of PLWD dependence level | Caregiver | T1 |
PLWD Quality of life as rated by CG (primary outcome) | QOL-AD [32] | 12 domains | Caregiver | T1, T2 |
Sleep Wake disorder | Actigraph [33] | WASO, TST, day/night sleep ratio, number of night awakenings | PLWD | T1, T2 |
Subjective sleep PLWD | PROMIS Sleep Related Impairment [34] | Symptoms of sleep impairment in PLWD | Caregiver | T1, T2 |
Subjective sleep of caregiver | Pittsburgh Sleep Quality Index (PSQI) [35] | Sleep quality rating | Caregiver | T1, T2 |
HPA Axis activity (possible mechanism) | Diurnal stress across the day | PLWD | T1, T2 | |
Demographics (descriptive, possible covariate) | Caregiver and PLWD Information (US Census + other sources) | Basic background characteristics | Caregiver | T1 |
Medications (descriptive, possible covariate) | PLWD medications | Brown bag review of prescription and non-prescription meds | Brown bag review | Nurse visit |
PLWD physical health (descriptive, possible covariate) | Charlson Comorbidity Index [37] | CG Proxy report of health | Caregiver | T1 |
Neuropsychiatric Behaviors (secondary outcome) | Neuropsychiatric Inventory (NPI) [38] | For each NPI behavior, CG rates upset (0 = no upset to 4 = very upset); Vigilance items ask CG to estimate time spent in care (alpha = .89) | Caregiver | T1, T2 |
Caregiver strain (secondary outcome) | Zarit Burden Interview (12) [39] | Caregiver burden | Caregiver | T1, T2 |
CG Depressive symptoms (potential moderator) | CES-D short form [40] | 10-items; sensitive to change; Cut off for depression ≥8 | Caregiver | T1, T2 |
Evaluation of study/ Quality control (descriptive, quality control) | Program Evaluation (Adapted from investigator’s previous studies) | Caregiver satisfaction with and utility of intervention; quality assurance | Caregiver | Telephone survey following T3 |