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Table 4 Associate between FRS at baseline (wave 1) and combined mortality and incident frailty during the follow-up (wave2-wave3)

From: The Framingham risk score is associated with incident frailty, or is it?

 

Model 1 a

Model 2 b

Model 3 c

HR (95% CI)

p Value

HR (95% CI)

p Value

HR (95% CI)

p Value

Generalized FRS [2008] (n=3,033)

1.06 (1.04 to 1.09)

<0.001

1.05 (1.02 to 1.08)

<0.001

1.02 (0.99 to 1.05)

0.327

Generalized FRS [2008] after excluding incident CVD (n=2,794)

1.06 (1.03 to 1.09)

<0.001

1.05 (1.02 to 1.09)

<0.001

1.01 (0.98 to 1.05)

0.381

Generalized FRS [2008] after excluding baseline depression (n=2,407)

1.08 (1.04 to 1.11)

<0.001

1.07 (1.03 to 1.11)

<0.001

1.03 (1.00 to 1.07)

0.078

Updated FRS [2015]d (n=3,033)

1.16 (1.11 to 1.21)

<0.001

1.13 (1.08 to 1.19)

<0.001

1.04 (0.98 to 1.10)

0.198

  1. aAdjusted for sex
  2. bAdjusted for sex, education, marital status, obesity, comorbidity burden, cognitive function score
  3. cAdjusted for sex, age, education, marital status, obesity, comorbidity burden, cognitive function score
  4. dUpdated FRS algorithm https://www.thecalculator.co/health/Framingham-Risk-Score-Calculator-for-Coronary-Heart-Disease-745.html