Table 2 Association between each cardiovascular disease risk factor at baseline (wave 1) and incident frailty during the follow-up (wave2-wave3). (n=2,901)
From: The Framingham risk score is associated with incident frailty, or is it?
| Sex-adjusted Model b | Fully-adjusted Model c | |||
|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | |
| Age (years) | 1.09 (1.07 to 1.11) | <0.001 | 1.08 (1.06 to 1.10) | <0.001 |
| Sex | ||||
| Male | 1 (ref) | 1 (ref) | ||
| Female | 1.73 (1.31 to 2.27) | <0.001 | 1.41 (1.00 to 1.98) | 0.049 |
| Total cholesterol (mg/dl) a | 0.76 (0.66 to 0.89) | <0.001 | 0.83 (0.71 to 0.96) | 0.006 |
| HDL cholesterol (mg/dl) a | 1.08 (0.96 to 1.22) | 0.155 | 1.05 (0.93 to 1.19) | 0.544 |
| Systolic blood pressure (mm Hg) a | 0.98 (0.85 to 1.12) | 0.610 | 0.93 (0.82 to 1.07) | 0.299 |
| Antihypertensive treatment | ||||
| No | 1 (ref) | 1 (ref) | ||
| Yes | 1.17 (0.89 to 1.55) | 0.266 | 1.31 (1.96 to 1.79) | 0.087 |
| Smoking | ||||
| No | 1 (ref) | 1 (ref) | ||
| Yes | 1.37 (1.03 to 1.83) | 0.031 | 1.42 (1.04 to 1.95) | 0.029 |
| Diabetes | ||||
| No | 1 (ref) | 1 (ref) | ||
| Yes | 1.06 (0.78 to 1.43) | 0.731 | 1.17 (0.84 to 1.62) | 0.358 |