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Table 1 Characteristics of study sample by baseline frailty status (n= 3,618a)

From: The Framingham risk score is associated with incident frailty, or is it?

Characteristic

All

Frailty status at baseline

Not-frail

Frail

P Value

n=3,313(91.6)

n=305 (8.4)

Age (years), mean (SD)

67.7 (6.5)

67.4 (6.2)

71.9 (7.7)

<0.001

Sex, n(%)

 Male

1,835 (50.7)

1,686 (50.9)

149 (48.9)

0.496

 Female

1,783 (49.3)

1,627 (49.1)

156 (51.2)

 

Framingham risk score, mean (SD)

15.1 (4.5)

15.1 (4.5)

15.55 (4.7)

0.096

Total cholesterol (mg/dl), mean (SD)

194.6 (38.5)

194.8 (38.3)

192.1 (40.3)

0.245

HDL cholesterol (mg/dl), mean (SD)

52.3 (15.7)

52.16 (15.6)

54.2 (16.2)

0.031

SBP (mm Hg), mean (SD)

135.1 (22.8)

135.0 (22.5)

136.6 (25.8)

0.236

Antihypertensive treatment, n (%)

 No

2,870 (79.3)

2,620 (79.1)

250 (82.0)

0.234

 Yes

748 (20.7)

693 (20.9)

55 (18.0)

 

Smoking, n (%)

 No

2,467 (68.2)

2,252 (68.0)

215 (70.5)

0.366

 Yes

1,151 (31.8)

1,061 (32.0)

90 (29.5)

 

Diabetes, n (%)

 No

3,061 (84.6)

2,796 (84.4)

265 (86.9)

0.249

 Yes

557 (15.4)

517 (15.6)

40 (13.1)

 

Education, n (%)

 Illiterate

1,399 (38.7)

1,234 (37.3)

165 (54.1)

<0.001

 Elementary school

1,643 (45.4)

1,524 (46.0)

119 (39.0)

 

 Middle school

410 (11.3)

391 (11.8)

19 (6.2)

 

 High school or above

164 (4.5)

162 (4.9)

2 (0.7)

 

Current residence, n (%)

 Rural

2,464 (68.1)

2,230 (67.3)

234 (76.7)

0.001

 Urban

1,154 (31.9)

1,083 (32.7)

71 (23.3)

 

Marital status, n (%)

 Married

2,899 (80.1)

2,689 (81.2)

210 (68.9)

<0.001

 Divorced

47 (1.3)

42 (1.3)

5 (1.6)

 

 Widowed

638 (17.6)

552 (16.7)

86 (18.2)

 

 Never married

34 (0.9)

30 (0.9)

4 (1.3)

 

Obese, n (%)

 No

3,301 (91.2)

3,022 (92.6)

279 (93.9)

0.400

 Yes

259 (7.3)

241 (7.4)

18 (6.1)

 

Cognitive functionb, mean (SD)

10.15 (4.2)

10.35 (4.1)

7.79 (4.0)

<0.001

Depressive symptoms scores c, mean (SD)

7.68 (5.3)

7.37 (5.2)

11.04 (5.4)

<0.001

Comorbidity burden d, mean (SD)

1.35 (1.3)

1.31 (1.3)

1.80 (1.4)

<0.001

  1. Abbreviations: SBP systolic blood pressure, CVD cardiovascular disease, SD standard deviation, HDL high density lipoprotein cholesterol
  2. abefore excluding missing data on frailty at follow-up waves (n=490) and prevalent frailty at baseline (n=227)
  3. bCognitive function was measured by the modified mini-mental status examination
  4. cDepressive symptoms was measured by the 10-item Center for Epidemiologic Studies Depression Scale
  5. dComorbidity includes cancer[excluding minor skin cancers], chronic lung diseases, liver disease, kidney disease, stomach or other digestive disease, arthritis/rheumatism and asthma