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Table 1 Baseline characteristics of the included patients

From: Pre-stroke cognitive impairment is associated with vascular imaging pathology: a prospective observational study

 

N

Overall

N = 410

Female

N = 182

Male

N = 228

p-value

Age at stroke, years (mean (±SD))

410

73.6 (±11)

75.0 (±12)

72.5 (±11)

0.003

Living alone (N(%))

410

152 (37.0)

88 (48.0)

64 (28.0)

0.05

Education (mean years(±SD))

410

12.1 (±4)

11.4 (±3)

12.7 (±4)

0.0001

NIHSS at admission (0-42) (mean (±SD))

405

4.1 (±5)a

4.3 (±5)

3.9 (±5)

0.34

Hemorrhagic stroke (N(%))

395

27 (7.0)

12 (7.0)

15 (7.0)

0.56

Pre-stroke GDS (1-7) (mean (±SD))

407

1.5 (±1)

1.6 (±1)

1.5 (±1)

0.11

Pre-stroke mRS (0-6) (mean (±SD))

408

2.2 (±1)

2.4 (±1)

2.1 (±1)

0.005

TOAST classification (N)

368

368

166

202

0.282*

Large vessel disease

 

39 (10.6)

14 (8.3)

25 (12.4)

 

Cardioembolic disease

 

84 (22.8)

33 (19.9)

51 (25.3)

 

Small vessel disease

 

89 (24.2)

39 (23.5)

50 (24.8)

 

Other etiology

 

7 (1.9)

4 (2.4)

3 (1.5)

 

Undetermined etiology

 

149 (40.5)

76 (45.8)

73 (36.1)

 

History of:

 Atrial fibrillation (N(%))

407

65 (16.0)

25 (14.0)

40 (18.0)

0.06

 Diabetes (N(%))

407

77 (19.0)

34 (19.0)

43 (19.0)

0.31

 Hypertension (N(%))

410

196 (48.0)

82 (45.0)

114 (50.0)

0.02

 Hypercholesterolemia (N(%))

407

155 (38.1)

61 (33.7)

94 (41.6)

0.103

 Previous stroke (N(%))

410

66 (16.0)

22 (12.0)

44 (19.0)

0.01

  1. Values are displayed as means (SD) and frequencies (%) for all patients and grouped by sex. Values are mean (±SD) for continuous variables and N (%) for binary variables. For group comparisons we used we used Mann-Whitney U test for continuous variables and chi-square test for binary variables. NIHSS National Institutes of Health stroke scale, mRS modified Rankin Scale, GDS Global Deterioration Scale, SD standard deviation. Previous stroke is clinically acknowledged stroke. aThe median (IQR) of the NIHSS was 3 (0 to 24). *p-value of chi-squared test of TOAST classification contingency table