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Table 1 Baseline characteristics for nursing home residents in total, and by group

From: The longitudinal association between the use of antihypertensive medications and 24-hour sleep in nursing homes: results from the randomized controlled COSMOS trial

 

Control group

Intervention group

Both groups

Mean/

(SD)/

N

Mean/

(SD)/

N

Mean/

(SD)/

N

n/

(%)/

n/

(%)/

n/

(%)/

median

(IQRa)

median

(IQRa)

median

(IQRa)

Demographic variables:

 Females

26

(67%)

39

43

(84%)

51

69

(77%)

90

 Age

85.3

(7.6)

39

88.2

(8.3)

51

87.0

(8.1)

90

 BMI

23.5

(4.6)

32

24.0

(3.9)

48

23.8

(4.2)

80

 Systolic blood pressureb

128

(17)

37

130

(18)

49

129

(18)

86

 Diastolic blood pressureb

70

(13)

37

70

(12)

49

70

(12)

86

 Activities of daily livingc

17.0

(5.5)

39

17.8

(.15)

51

17.3

(5.3)

90

 Regular prescriptions

7.5

(4.0)

39

7..6

(3.9)

51

7.6

(3.9)

90

 Diagnoses

4.2

(2.0)

39

4.5

(2.9)

51

4.4

(2.6)

90

Cognitive function:

 MMSEa (0-30)

12

(7-17)

35

10

(5-13)

49

11

(5-16.5)

84

 No (24-30)

2

(6%)

 

3

(6%)

 

5

(6%)

 

 Mild (18-23)

6

(17%)

 

7

(14%)

 

13

(15%)

 

 Moderate (12-17)

10

(28%)

 

10

(21%)

 

20

(24%)

 

 Severe (0-11)

17

(49%)

 

29

(59%)

 

46

(55%)

 

Blood pressureb:

        

86

 Low (blood pressure < 120)

12

(32%)

 

12

(24%)

 

24

(28%)

 

 Normal (120 ≤ blood pressure < 141)

18

(49%)

 

25

(52%)

 

43

(50%)

 

 High (blood pressure ≥ 141)

7

(19%)

 

12

(24%)

 

19

(22%)

 

Hypertension diagnoses:

 Elevated blood pressure (K85)

1

(3%)

39

1

(2%)

51

2

(2%)

90

 Uncomplicated hypertension (K86)

11

(28%)

39

13

(25%)

51

24

(27%)

90

 Hypertension with organ complications (K87)

1

(3%)

39

2

(4%)

51

3

(3%)

90

Medication (ATC Code):

 Antihypertensive medications

21

(54%)

39

26

(51%)

51

47

(52%)

90

 High-ceiling diuretics (C03C)

13

(33%)

39

13

(25%)

51

26

(29%)

90

 Beta-blockers (C07A)

13

(33%)

39

14

(27%)

51

27

(30%)

90

 Plain angiotensin II antagonists (C09C)

3

(8%)

39

9

(18%)

51

12

(13%)

90

 Plain ACE inhibitors (C09A)

3

(8%)

39

2

(4%)

51

5

(6%)

90

 Calcium channel blockers, mainly vascular effect (C08C)

2

(5%)

39

5

(10%)

51

7

(8%)

90

Sleepa:

 Total sleep time (TST)

443

(348-552)

37

514

(425-601)

46

492

(371-572)

83

 Sleep onset latency (SOL)

24

(10-95)

37

23

(10-64)

46

24

(10-79)

83

 Wake after sleep onset

149

(105-193)

37

127

(82-202)

46

142

(93-202)

83

 Daytime sleep (DTS)

170

(102-237)

37

115

(204-342)

45

180

(110-276)

82

 Early morning awakening (EMA)

39

(31-73)

37

28

(14-56)

46

35

(19-70)

83

  1. Data are presented as mean (SD), number (%) or median (IQR), with score ranges in parentheses
  2. aInter Quartile Range
  3. bMeasured in mmHg
  4. cMeasured on a scale from 0 to 30, where 0 is independent and 30 is totally independent in activities of daily living
  5. dHigher scores indicate better cognitive function
  6. eReported as average minutes per day/night
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