GRSs | OR (95%CI) for MS | P | OR (95%CI) for T2D | P | OR (95%CI) for abnormal SBP | P | OR (95%CI) for abnormal DBP | P |
---|---|---|---|---|---|---|---|---|
GRSsynthesis | ||||||||
 ORZY [per 1 unit higher in GRS] | 1.21(0.88–1.66) | 0.497 | 1.07(1.01–1.42) | 0.048* | 1.35(0.85–1.84) | 0.435 | 1.16(1.02–1.65) | 0.003* |
 ORIV [per 25 nmol/L decrease 25(OH) D concentration] | 0.85(0.56–1.28) | 0.586 | 1.10(1.02–1.45) | 0.014* | 0.76(0.51–1.31) | 0.141 | 1.14(1.03–1.43) | 0.019* |
GRSmetabolism | ||||||||
 ORZY [per 1 unit higher in GRS] | 1.06(0.79–1.44) | 0.337 | 0.97(0.66–1.43) | 0.646 | 0.92(0.73–1.17) | 0.652 | 1.13(0.86–1.48) | 0.627 |
 ORIV [per 25 nmol/L decrease 25(OH) D concentration] | 0.92(0.69–1.22) | 0.159 | 0.91(0.60–1.36) | 0.742 | 1.04(0.74–1.45) | 0.371 | 0.83(0.62–1.10) | 0.579 |
GRScombined | ||||||||
 ORZY [per 1 unit higher in GRS] | 1.05(0.83–1.32) | 0.224 | 1.16(0.67–1.51) | 0.154 | 0.79(0.60–1.02) | 0.743 | 1.03(0.73–1.15) | 0.085 |
 ORIV [per 25 nmol/L decrease 25(OH) D concentration] | 1.04(0.70–1.53) | 0.457 | 0.92(0.70–1.02) | 0.082 | 0.88(0.67–1.15) | 0.628 | 1.05(1.00–1.49) | 0.046* |