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Fig. 2 | BMC Geriatrics

Fig. 2

From: Association of serum 25-hydroxyvitamin D with metabolic syndrome and type 2 diabetes: a one sample Mendelian randomization study

Fig. 2

Scatterplot of associations of per allele effects of the four SNPs with risk of MS/T2D. This association was evaluated for 25(OH) D concentrations in our population based on the effect of the SNPs on 25(OH) D concentration (Square: CYP2R1 − rs10741657; Circle: DHCR7 − rs12785878; Triangle: GC/DBP − rs2282679; Diamond: CYP24A1 − rs6013897). *: P < 0.05. Dashed line: The slope from an inverse-variance weighted linear regression of per allele lnOR for MS/T2D for all four SNPs on 25(OH) D concentrations, with the line forced through the origin. Fulled line: The slope from an inverse-variance weighted linear regression of per allele lnOR for MS/T2D for two synthesis SNPs on 25(OH) D concentrations, with the line forced through the origin

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