Table 1 Study Flowchart
Assessment | Eligibility | Pre-baseline | Baseline | Interim | Interim | Pre-final | Final |
|---|---|---|---|---|---|---|---|
Week of intervention | 1 | 3–5 | 7–9 | 11–12 | 12 | ||
Visit modality | Video call | Video call | Telephone | Telephone | Telephone | Video call | |
Inclusion/Exclusion Criteria checks | X | ||||||
Participant information and informed consent | X | X | |||||
Randomisation | X | ||||||
Postal box sent out | X | ||||||
3-day food diary (post/online) | X | X | |||||
Questionnaire (post/online) | X | X | |||||
CANTAB cognitive test (online) | X | X | |||||
Provide supplements (post) | X | ||||||
Faecal sample (post) | X | X | |||||
Capillary blood sample (post) | X | X | |||||
Urine sample (post) | X | X | |||||
Saliva sample (post) | X | X | |||||
Short Physical Performance Battery | X | X | |||||
Weight (kg) – if scales available | X | X | |||||
Height (cm) | X | X | |||||
Check compliance/ adverse effects | X | X | |||||
Participants to count leftover supplement sachets | X |