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Table 3 Risk of developing urinary tract infection and urosepsis according to the severity of frailty of participants

From: Frailty increases the risk for developing urinary tract infection among 79,887 patients with diabetic mellitus and chronic kidney disease

Outcomes

Events

Person-year

Incidence density*

Crude

Model A&

Model B#

HR

95 % CI

HR

95 % CI

HR

95 % CI

Urinary tract infection

        

No FRAIL item

2,934

110,373.7

26.6

1

-

1

-

1

-

1 item

6,314

137,015.7

46.1

1.70

1.63–1.77a

1.19

1.12–1.26a

1.14

1.08–1.21a

2 items

1,778

31,590.2

56.3

2.03

1.92–2.16a

1.24

1.16–1.34a

1.16

1.08–1.25a

≥ 3 items

149

1,723.1

86.5

3.03

2.57–3.58a

1.43

1.21–1.70a

1.28

1.06–1.53b

Per 1 item increase

   

1.45

1.41–1.49a

1.11

1.08–1.15a

1.07

1.04–1.11a

Urinary tract infection with sepsis

        

No FRAIL item

699

110,869.5

6.3

1

-

1

-

1

-

1 item

1,910

138,441.3

13.8

2.20

2.02–2.40a

1.07

0.95–1.19

1.004

0.90–1.12

2 items

559

31,917.7

17.5

2.80

2.51–3.13a

1.13

0.98–1.29

1.005

0.88–1.15

≥ 3 items

53

1782.0

29.7

4.79

3.62–6.33a

1.18

0.88–1.59

1.048

0.77–1.42

Per 1 item increase

   

1.68

1.60–1.76a

1.06

0.995–1.13

1.008

0.95–1.07

  1. * per 1000 patient-year
  2. & Incorporating all variables in Table 1
  3. # Model A with competing risk analysis for mortality
  4. a p < 0.001
  5. b p < 0.01