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Table 2 Weighted pooled prevalence (WPP) of comorbidities, clinical features, severity of illness and outcome in older patients with COVID-19

From: Clinical features and outcomes of COVID-19 in older adults: a systematic review and meta-analysis

Variable Number of studies Number of patients WPP 95% CI p-value for Cochran’s Q I2 Egger’s test* (p-value)
Severity of illness
 Severe 18 2049 0.50 0.36–0.65 0.00 95 < 0.001
 Critical 14 5280 0.23 0.16–0.31 0.00 88 < 0.001
Outcomes
 Discharged 14 6901 0.43 0.03–0.88 0.00 100 < 0.001
 Dead 30 12,060 0.11 0.04–0.20 0.00 98 < 0.001
Comorbidities
  ≥ 1 comorbidity 12 1888 0.81 0.68–0.93 0.00 92 < 0.001
 Hypertension 17 2245 0.48 0.36–0.60 0.00 92 < 0.001
 Diabetes Mellitus 17 1804 0.22 0.13–0.32 0.00 86 0.004
 Cardiovascular disease 13 1679 0.19 0.11–0.28 0.00 85 0.002
 Hypothyroid 3 99 0.11 0.01–0.25 0.16 45 ..
 Neurological disease 9 871 0.09 0.06–0.13 0.02 55 ..
 Malignancy 12 1476 0.09 0.03–0.15 0.00 80 0.014
 Chronic lung disease 14 1748 0.08 0.03–0.13 0.00 82 0.004
 Cerebrovascular  disease 9 814 0.08 0.06–0.11 0.23 24 ..
 Kidney disease 14 1591 0.05 0.01–0.09 0.00 77 0.066
 Liver disease 11 1416 0.03 0.01–0.05 0.01 58 0.018
 Autoimmune diseases 3 473 0.02 0.00–0.06 0.06 65 ..
Clinical Features
 Fever 11 782 0.83 0.66–0.97 0.00 91 < 0.001
 Cough 11 782 0.60 0.50–0.70 0.00 71 < 0.001
 Dry cough 4 432 0.56 0.43–0.69 0.08 56 ..
 Sputum production 8 654 0.28 0.17–0.39 0.00 70 ..
 Dyspnoea 11 782 0.42 0.19–0.67 0.00 94 0.020
 Fatigue 9 691 0.33 0.16–0.52 0.00 88 ..
 Anorexia 3 470 0.31 0.01–0.67 0.00 96 ..
 Chest discomfort 5 500 0.26 0.01–0.57 0.00 93 ..
 Diarrhoea 6 575 0.18 0.02–0.39 0.00 91 ..
 Myalgia 9 746 0.15 0.01–0.33 0.00 93 ..
 Abdominal pain 4 219 0.11 0.02–0.22 0.00 80 ..
 Sore Throat 5 639 0.10 0.00–0.25 0.00 94 ..
 Headache 7 714 0.09 0.00–0.24 0.00 94 ..
 Nausea-Vomiting 4 543 0.08 0.00–0.23 0.00 93 ..
 Gastrointestinal symptoms 3 169 0.15 0.00–0.79 0.00 94 ..