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Table 5 Linear regression analysis of log transformed serum sodium levels and quintiles of cognitive test scores stratified by serum sodium levels

From: Serum sodium in relation to various domains of cognitive function in the elderly US population

Model CERAD WLT-IR CERAD WLT-DR AFT DSST
Beta ± SE P Beta ± SE P Beta ± SE P Beta ± SE P
Hyponatremia (<135 mmol/L)
 n 87 87 86 81
 Unadjusted 5.36 ± 12.62 0.674 3.17 ± 12.43 0.800 3.57 ± 11.78 0.764 9.84 ± 10.99 0.379
 Model 1a 17.51 ± 12.67 0.179 15.96 ± 11.08 0.162 -1.39 ± 8.56 0.873 2.74 ± 10.12 0.789
Normal serum sodium (135-145 mmol/L)
 n 2446 2445 2428 2376
 Unadjusted 2.50 ± 3.04 0.418 4.35 ± 3.06 0.164 -1.20 ± 2.08 0.569 -1.03 ± 2.13 0.632
 Model 1a 3.16 ± 2.80 0.267 5.61 ± 3.03 0.074 1.08 ± 2.19 0.625 0.22 ± 1.75 0.900
  1. a Adjusted for sex, age, marital status, ethnicity, smoking status, alcohol consumption, physical activity, income, obesity, education, GFR, serum glucose levels, diabetes, CVD, COPD, thyroid disease, and liver disease