Serum sodium in relation to various domains of cognitive function in the elderly US population

BMC Geriatrics

Table 5 Linear regression analysis of log transformed serum sodium levels and quintiles of cognitive test scores stratified by serum sodium levels

Model	CERAD WLT-IR		CERAD WLT-DR		AFT		DSST
Model	Beta ± SE	P	Beta ± SE	P	Beta ± SE	P	Beta ± SE	P
Hyponatremia (<135 mmol/L)
n	87		87		86		81
Unadjusted	5.36 ± 12.62	0.674	3.17 ± 12.43	0.800	3.57 ± 11.78	0.764	9.84 ± 10.99	0.379
Model 1^a	17.51 ± 12.67	0.179	15.96 ± 11.08	0.162	-1.39 ± 8.56	0.873	2.74 ± 10.12	0.789
Normal serum sodium (135-145 mmol/L)
n	2446		2445		2428		2376
Unadjusted	2.50 ± 3.04	0.418	4.35 ± 3.06	0.164	-1.20 ± 2.08	0.569	-1.03 ± 2.13	0.632
Model 1^a	3.16 ± 2.80	0.267	5.61 ± 3.03	0.074	1.08 ± 2.19	0.625	0.22 ± 1.75	0.900

^a Adjusted for sex, age, marital status, ethnicity, smoking status, alcohol consumption, physical activity, income, obesity, education, GFR, serum glucose levels, diabetes, CVD, COPD, thyroid disease, and liver disease

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