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Table 4 Linear regression analysis of log-transformed serum sodium levels and quintiles of cognitive test scores by hyponatremia and hypernatremia status

From: Serum sodium in relation to various domains of cognitive function in the elderly US population

  n Unadjusted model Adjusted model a
  Beta ± SE P Beta ± SE P
CEARD WLT-IR
 Normal 2446 1   1  
 Hyponatremia 87 -0.58 ± 0.18 0.002 -0.34 ± 0.15 0.035
 Hypernatremia 8 0.39 ± 0.67 0.565 0.13 ± 0.68 0.852
CEARD WLT-DR
 Normal 2445 1   1  
 Hyponatremia 87 -0.69 ± 0.15 <0.001 -0.48 ± 0.10 <0.001
 Hypernatremia 8 0.60 ± 0.59 0.318 0.42 ± 0.62 0.496
AFT
 Normal 2428 1   1  
 Hyponatremia 86 -0.62 ± 0.19 0.002 -0.38 ± 0.19 0.052
 Hypernatremia 9 -0.63 ± 0.65 0.334 -0.69 ± 0.44 0.127
DSST
 Normal 2376 Reference Reference
 Hyponatremia 81 -0.52 ± 0.23 0.030 -0.18 ± 0.21 0.382
 Hypernatremia 8 0.23 ± 0.47 0.620 0.07 ± 0.41 0.866
  1. aAdjusted for sex, age, marital status, ethnicity, smoking status, alcohol consumption, physical activity, income, obesity, education, GFR, serum glucose levels, diuretics use, diabetes, CVD, stroke, COPD, thyroid disease, and liver disease