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Table 4 Detailed drug utilization: Details of cohort for those who experienced a prescribing cascade

From: An examination of three prescribing cascades in a cohort of older adults with dementia

Prescribing Cascade 1 2 3
Medication class Cholinesterase inhibitor (N06DA) Bladder Anticholinergic (G04BD) Metoclopramide (A03FA01) Parkinson’s Disease medication (N04B) CCB (C08CA) Diuretic (C03)
Number of cases of prescribing cascade 60 11 289
Mean age at dementia diagnosis for NSSPBD in prescribing cascade, years (SD) 79.0 (7.4) 80.9 (8.0) 82.8 (7.7)
Implicated medication Donepezil – 40 (66.7%)
Galantamine, Rivastigmine – 20 (33.3%)
Oxybutynin – 43 (71.7%)
Tolterodine, Solifenacin,
Trospium, Darifenacin,
Fesoterodine – 28.3%
Metoclopramide – 11 (100%) Levodopa and decarboxylase inhibitor, Ropinirole, Pramipexole – 11 (100%) Amlodipine – 193 (66.8%)
Felodipine – 10 (3.5%)
Nifedipine – 86 (29.8%)
Furosemide – 224 (77.5%)
Hydrochlorothiazide – 41 (14.2%)
Ethacrynic acid, Spironolactone, Amiloride – 24 (8.3%)
  1. NSSPBD Nova Scotia Seniors’ Pharmacare Beneficiaries with Dementia, SD standard deviation